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大量儿童和青少年样本中乳制品摄入量与哮喘症状的关系:一项横断面研究。

Dairy intake in association with asthma symptoms among a large sample of children and adolescents: a cross-sectional study.

作者信息

Jamalvandi Mona, Sasanfar Bahareh, Nafei Zahra, Behniafard Nasrin, Jafari Marjan, Salehi-Abargouei Amin

机构信息

Research Center for Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Front Nutr. 2024 Mar 21;11:1298704. doi: 10.3389/fnut.2024.1298704. eCollection 2024.

Abstract

BACKGROUND AND OBJECTIVE

Dairy products may be associated with an increased risk of asthma, although there is little scientific evidence to support this association. The goal of this study was to explore the association between dairy consumption and asthma symptoms.

MATERIALS AND METHODS

This cross-sectional study was conducted on children and adolescents aged 6-8 and 13-14 years living in central Iran. Dietary food consumption was assessed using a multiple-choice questionnaire. Logistic regression was used to obtain odds ratios for the association between milk, other dairy products, and total dairy consumption with the risk of asthma symptoms.

RESULTS

In total, 7,667 participants (3,414 boys and 4,253 girls) were included in the current study. Milk intake and total dairy consumption were not associated with the likelihood of wheezing, asthma confirmed by a doctor, current asthma, and asthma medication use. In addition, there was no association between other dairy product intake and the odds of wheezing in the past 12 months in the crude model. However, after adjusting for several confounders, those in the top category had lower odds of wheezing in the past 12 months than those in the bottom category (OR: 0.58; 95% CI: 0.40-0.85).

CONCLUSION

The consumption of dairy products other than milk, including cheese and yogurt, might reduce the likelihood of wheezing in children and adolescents.

摘要

背景与目的

乳制品可能与哮喘风险增加有关,尽管几乎没有科学证据支持这一关联。本研究的目的是探讨乳制品消费与哮喘症状之间的关联。

材料与方法

这项横断面研究针对居住在伊朗中部的6 - 8岁和13 - 14岁儿童及青少年开展。使用多项选择题问卷评估饮食食物消费情况。采用逻辑回归分析来获取牛奶、其他乳制品以及总乳制品消费量与哮喘症状风险之间关联的比值比。

结果

本研究共纳入7667名参与者(3414名男孩和4253名女孩)。牛奶摄入量和总乳制品消费量与喘息、医生确诊哮喘、当前哮喘以及使用哮喘药物的可能性无关。此外,在粗模型中,其他乳制品摄入量与过去12个月内喘息几率之间也无关联。然而,在对多个混杂因素进行调整后,处于最高类别者过去12个月内喘息几率低于最低类别者(比值比:0.58;95%置信区间:0.40 - 0.85)。

结论

除牛奶外的乳制品(包括奶酪和酸奶)消费可能会降低儿童和青少年喘息的可能性。

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Which Wheezing Preschoolers Should be Treated for Asthma?哪些喘息的学龄前儿童应该接受哮喘治疗?
J Allergy Clin Immunol Pract. 2021 Jul;9(7):2611-2618. doi: 10.1016/j.jaip.2021.02.045. Epub 2021 Mar 4.
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Recent findings in the genetics and epigenetics of asthma and allergy.哮喘和过敏的遗传学和表观遗传学的最新发现。
Semin Immunopathol. 2020 Feb;42(1):43-60. doi: 10.1007/s00281-019-00777-w. Epub 2020 Feb 14.

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