Aggarwal Kanishk, Bansal Vasu, Mahmood Ramsha, Kanagala Sai Gautham, Jain Rohit
From the Dayanand Medical College and Hospital, Ludhiana, India.
Avalon University School of Medicine, Willemstad, Curacao.
Cardiol Rev. 2025;33(3):219-226. doi: 10.1097/CRD.0000000000000600. Epub 2023 Aug 18.
Asthma and cardiovascular diseases (CVDs) are the 2 common and complex health problems with a substantial global impact. Epidemiological studies indicate that asthma and CVDs are common, with evidence supporting their cooccurrence. Inflammation, oxidative stress, obesity, metabolic syndrome, smoking, secondhand smoke exposure, physical inactivity, and environmental exposures are all risk factors for asthma and CVDs. In addition, inflammatory and immunological pathways, autonomic dysfunction, endothelial dysfunction, thrombosis, coagulation, and common genetic risk factors contribute to the asthma-CVD relationship. Asthmatic individuals have higher morbidity and mortality rates related to CVDs and high-risk factors. Techniques such as screening for CVDs in asthma patients, pharmaceutical therapy, and lifestyle changes are critical for effectively managing these comorbid illnesses. Understanding the link between asthma and CVD is necessary for integrated and clinical management approaches to enhance patient outcomes and lessen the burden of these related diseases.
哮喘和心血管疾病(CVDs)是两种常见且复杂的健康问题,在全球具有重大影响。流行病学研究表明,哮喘和心血管疾病很常见,有证据支持它们同时出现。炎症、氧化应激、肥胖、代谢综合征、吸烟、接触二手烟、身体活动不足和环境暴露都是哮喘和心血管疾病的危险因素。此外,炎症和免疫途径、自主神经功能障碍、内皮功能障碍、血栓形成、凝血以及常见的遗传危险因素也促成了哮喘与心血管疾病之间的关系。哮喘患者因心血管疾病和高危因素而具有更高的发病率和死亡率。诸如对哮喘患者进行心血管疾病筛查、药物治疗和生活方式改变等技术对于有效管理这些合并症至关重要。了解哮喘与心血管疾病之间的联系对于采用综合临床管理方法以改善患者预后并减轻这些相关疾病的负担而言是必要的。