Bhardwaj Vibha
Environment Laboratories, Ras Al Khaimah Municipality, Ras Al Khaimah, UAE.
Adv Exp Med Biol. 2025;1476:1-8. doi: 10.1007/5584_2023_786.
This study investigates the in vitro antibacterial activity of coconut oil on selected clinical and pure bacterial isolates. Clinical samples were isolated from the people of Ras Al Khaimah, United Arab Emirates. Biochemical examination of the microorganisms was done according to standard methods. Pure bacterial cultures were provided from LTA srl Italia. In this research work, an effort has been made to highlight the valuable properties of Cocos nucifera oil, in order to rationalize the use of coconut oil against bacteria. Experiments were performed by agar well diffusion method. Ciprofloxacin was used as a standard antibiotic. The assay of antibacterial activity of clinical isolate of Streptococcus species showed the highest susceptibility to coconut oil while Escherichia coli had the least. This study endorses the use of coconut oil as therapeutic agent since it contains lauric acid which is bactericidal. The utilization of coconut oil should be promoted as a functional food and the use of coconut seed flesh in our diets should be encouraged for health-supporting functions. Further studies should be done on the oil and its derivatives both in vitro and in vivo to unveil their mechanism of action.
本研究调查了椰子油对选定临床分离菌和纯细菌分离株的体外抗菌活性。临床样本取自阿拉伯联合酋长国拉斯海马的人群。微生物的生化检测按照标准方法进行。纯细菌培养物由意大利LTA srl公司提供。在这项研究工作中，人们致力于突出椰油的宝贵特性，以便合理使用椰子油对抗细菌。实验采用琼脂孔扩散法进行。环丙沙星用作标准抗生素。链球菌临床分离株的抗菌活性测定显示对椰子油的敏感性最高，而大肠杆菌的敏感性最低。本研究支持将椰子油用作治疗剂，因为它含有具有杀菌作用的月桂酸。应推广将椰子油用作功能性食品，并鼓励在我们的饮食中使用椰果肉以发挥其健康支持功能。应进一步对该油及其衍生物进行体外和体内研究，以揭示其作用机制。
