Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Department of Biology, College of Science, Shantou University, Shantou 515063, Guangdong, China.
Biomed Pharmacother. 2023 Oct;166:115320. doi: 10.1016/j.biopha.2023.115320. Epub 2023 Aug 17.
The COVID-19 pandemic has caused significant global impact, resulting in long-term health effects for many individuals. As more patients recover, there is a growing need to identify effective management strategies for ongoing health concerns, such as post-COVID-19 syndrome, characterized by persistent symptoms or complications beyond several weeks or months from the onset of symptoms. In this review, we explore the potential of dietary polysaccharides as a promising approach to managing post-COVID-19 syndrome. We summarize the immunomodulatory, antioxidant, antiviral, and prebiotic activities of dietary polysaccharides for the management of post-COVID-19 syndrome. Furthermore, the review investigates the role of polysaccharides in enhancing immune response, regulating immune function, improving oxidative stress, inhibiting virus binding to ACE2, balancing gut microbiota, and increasing functional metabolites. These properties of dietary polysaccharides may help alleviate COVID-19 symptoms, providing a promising avenue for effective treatment strategies.
新冠疫情大流行造成了重大的全球影响，导致许多人出现长期健康问题。随着越来越多的患者康复，人们越来越需要确定有效的管理策略，以应对持续存在的健康问题，例如新冠后综合征，其特征是在症状出现后数周或数月后仍存在持续症状或并发症。在这篇综述中，我们探讨了膳食多糖作为管理新冠后综合征的一种有前途的方法。我们总结了膳食多糖在管理新冠后综合征方面的免疫调节、抗氧化、抗病毒和益生元活性。此外，该综述还研究了多糖在增强免疫反应、调节免疫功能、改善氧化应激、抑制病毒与 ACE2 结合、平衡肠道微生物群和增加功能代谢物方面的作用。这些膳食多糖的特性可能有助于缓解新冠症状，为有效治疗策略提供了一个有希望的途径。
