Department of Food Engineering, Technology Centre, Federal University of Paraiba, João Pessoa, Paraiba, Brazil.
Animal Science Departament, Federal University of Paraiba, Areia, Paraiba, Brazil.
Behav Brain Res. 2023 Sep 13;453:114634. doi: 10.1016/j.bbr.2023.114634. Epub 2023 Aug 18.
This study aimed to evaluate the effect of cashew nut consumption on anxiety-like behavior in dyslipidemic rats. The groups formed were: Control (CONT), Dyslipidemic (DL) and Dyslipidemic cashew nuts (DLCN). Tests to assess anxiety parameters were performed after the treatment period. Brain fatty acid profiles were analyzed. The animals in the DLCN group showed more rearing than DL, without differing from the CONT and less grooming than either the DL and CONT in the Open Field. In the Elevated Plus Maze, DLCN spent more time on the open arms and in the central area compared to the other groups. As for brain fatty acids, there was a reduction in polyunsaturated fatty acids for the DLCN compared to the other groups. The cashew nut, rich in fatty acids, phenolic and flavonoid compounds, reduced the anxiogenic-like behavior caused by dyslipidemia in rats without altering brain fatty acids.
本研究旨在评估腰果摄入对血脂异常大鼠焦虑样行为的影响。形成的组为：对照组（CONT）、血脂异常组（DL）和血脂异常腰果组（DLCN）。在治疗期后进行评估焦虑参数的测试。分析脑脂肪酸谱。与 DL 和 CONT 相比，DLCN 组的动物在开放场中表现出更多的站立，但比 DL 组少，与 DL 和 CONT 相比，DLCN 组在高架十字迷宫中的修饰行为更少。在高架十字迷宫中，与其他组相比，DLCN 在开放臂和中央区域花费的时间更多。至于脑脂肪酸，与其他组相比，DLCN 的多不饱和脂肪酸减少。腰果富含脂肪酸、酚类和类黄酮化合物，可减少血脂异常大鼠的焦虑样行为，而不改变大脑脂肪酸。
