Kirby C R, Convertino V A
J Appl Physiol (1985). 1986 Sep;61(3):967-70. doi: 10.1152/jappl.1986.61.3.967.
This investigation was designed to determine the relationship between the levels of plasma aldosterone and eccrine sweat gland sodium excretion following exercise and heat acclimation. Ten subjects exercised at 45% of their maximal O2 uptake in a hot (40 degrees C), moderately humid (45% relative humidity) environment for 2 h/day on ten consecutive days. Acclimation was verified by significant reductions in exercise heart rate, rectal temperature, and heat storage, as well as significant elevation of resting plasma volume (12%, P less than 0.05) and exercise sweat rate on day 10 compared with day 1 of acclimation. During exercise, the concentration and total content of sodium in sweat as well as plasma aldosterone were significantly decreased from day 1 to day 10. The ratio of sweat sodium reabsorbed to plasma aldosterone concentration was significantly increased from day 1 to day 10 after both 1 and 2 h of exercise. These data indicate that plasma aldosterone concentrations decrease following heat acclimation; and eccrine gland responsiveness to aldosterone, as represented by sweat sodium reabsorption, may be augumented through exercise and heat acclimation.
本研究旨在确定运动及热适应后血浆醛固酮水平与外分泌汗腺钠排泄之间的关系。10名受试者在炎热（40℃）、中等湿度（相对湿度45%）环境中，以其最大摄氧量的45%进行运动，每天运动2小时，连续运动10天。通过运动心率、直肠温度和蓄热的显著降低，以及与适应第1天相比，第10天静息血浆量显著增加（12%，P<0.05）和运动出汗率显著升高来验证适应情况。运动期间，从第1天到第10天，汗液中钠的浓度和总量以及血浆醛固酮均显著降低。运动1小时和2小时后，从第1天到第10天，汗液重吸收的钠与血浆醛固酮浓度的比值均显著增加。这些数据表明，热适应后血浆醛固酮浓度降低；并且，以外分泌腺对醛固酮的反应性（以汗液钠重吸收表示）可能通过运动和热适应得到增强。
