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黏液性浆液性错构瘤的疑难病例。

Confounding case of seromucinous hamartoma.

机构信息

Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Pathology, Pittsburgh Veterans Affairs Medical Center, Pittsburgh, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2021 Mar 15;14(3):e240460. doi: 10.1136/bcr-2020-240460.

Abstract

A 67-year-old man presented with progressive diplopia. On evaluation, he was noted to have bilateral palsies of cranial nerves III, IV and VI as well as a unilateral right true vocal fold paralysis. CT and MRI studies demonstrated a T2-bright left ethmoid mass with no evidence of bony erosion. Direct visualisation demonstrated a polypoid appearing mass of the left sphenoethmoid recess. Operative biopsy was pursued with final pathology demonstrating benign seromucinous hamartoma. Subsequent blood work demonstrated high titres of anti-acetylcholine receptor antibodies consistent with myasthenia gravis. The patient was started on pyridostigmine with improvement in his ocular cranial neuropathies.

摘要

一位 67 岁男性因进行性复视就诊。评估时,发现他存在第三、第四和第六脑神经双侧麻痹以及右侧单侧真性声带麻痹。CT 和 MRI 研究显示左侧筛窦有 T2 亮区肿块,无骨侵蚀证据。直接可视化显示左侧蝶筛隐窝有息肉样肿块。行手术活检,最终病理诊断为良性浆液黏液性错构瘤。随后的血液检查显示乙酰胆碱受体抗体滴度高,符合重症肌无力。患者开始服用吡啶斯的明,其眼颅神经病得到改善。

相似文献

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Confounding case of seromucinous hamartoma.黏液性浆液性错构瘤的疑难病例。
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Myasthenia gravis mimicking unilateral vocal fold paralysis at presentation.重症肌无力在初诊时酷似单侧声带麻痹。
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本文引用的文献

1
Seromucinous Hamartoma of the Nasal Cavity.鼻腔浆液黏液性错构瘤
Head Neck Pathol. 2019 Jun;13(2):239-242. doi: 10.1007/s12105-018-0914-6. Epub 2018 Mar 28.
2
Sinonasal seromucinous hamartoma.鼻窦浆液黏液性错构瘤。
Eur Arch Otorhinolaryngol. 2018 Mar;275(3):743-749. doi: 10.1007/s00405-018-4885-8. Epub 2018 Jan 30.
4
Low grade glandular lesions of the sinonasal tract: a focused review.鼻旁窦低级别腺性病变:聚焦综述
Head Neck Pathol. 2010 Mar;4(1):77-83. doi: 10.1007/s12105-009-0159-5. Epub 2010 Jan 7.

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