Department of Hematology, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
Guang'an People's Hospital, Guang'an, 638001, Sichuan, People's Republic of China.
J Nanobiotechnology. 2023 Aug 22;21(1):288. doi: 10.1186/s12951-023-02060-5.
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique biological and physical properties. RBCs have demonstrated outstanding potential as delivery vehicles due to their low immunogenicity, long-circulating cycle, and immune characteristics, exhibiting delivery abilities. There have been several developments in understanding the delivery system of RBCs and their derivatives, and they have been applied in various aspects of biomedicine. This article compared the various physiological and physical characteristics of RBCs, analyzed their potential advantages in delivery systems, and summarized their existing practices in biomedicine.
红细胞（RBCs）是体内最丰富的细胞，具有独特的生物学和物理特性。由于其低免疫原性、长循环周期和免疫特性，红细胞具有出色的作为递药载体的潜力，表现出递药能力。人们对 RBC 及其衍生物的递药系统有了一些了解，并将其应用于生物医学的各个方面。本文比较了 RBC 的各种生理和物理特性，分析了其在递药系统中的潜在优势，并总结了其在生物医学中的现有应用。
