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脊髓刺激与血管内再通治疗糖尿病足溃疡的疗效比较:一项回顾性观察研究。

Comparison Between the Efficacy of Spinal Cord Stimulation and of Endovascular Revascularization in the Treatment of Diabetic Foot Ulcers: A Retrospective Observational Study.

机构信息

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China.

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China.

出版信息

Neuromodulation. 2023 Oct;26(7):1424-1432. doi: 10.1016/j.neurom.2023.07.007. Epub 2023 Aug 23.

DOI:10.1016/j.neurom.2023.07.007
PMID:37610397
Abstract

OBJECTIVE

We aimed to compare the effects of spinal cord stimulation (SCS) with those of endovascular revascularization on the treatment of diabetic foot ulcers.

MATERIALS AND METHODS

A total of 104 patients with diabetic foot ulcers who met the inclusion criteria were retrospectively analyzed and classified to the SCS treatment group (n = 46) and endovascular revascularization treatment group (n = 46). The quality-of-life scores (Quality of Life Scale for Patients with Liver Cancer v2.0), visual pain analog scale score, lower limb skin temperature, lower limb arterial ultrasound results, and lower extremity electromyography results were analyzed to compare the efficacy of the two treatments for diabetic foot ulcers in the two groups before surgery and six months after surgery.

RESULTS

A total of 92 patients (men: 73.9%, mean age: 66.51 ± 11.67 years) completed the six-month postoperative follow-up period. The patients in the SCS treatment group had a higher quality-of-life score (25.54% vs 13.77%, p < 0.05), a larger reduction in pain scores (69.18% vs 37.21%, p < 0.05), and a larger reduction in foot temperature (18.56% vs 7.24%, p < 0.05) than those of the endovascular revascularization treatment group at six months after surgery. The degree of vasodilation in the lower limbs on color Doppler arterial ultrasound and the nerve conduction velocity were higher in the SCS treatment group than in the endovascular revascularization treatment group at six months after surgery (p < 0.05).

CONCLUSION

SCS was more effective than endovascular revascularization in improving quality of life, relieving pain, improving lower limb skin temperature, increasing lower limb blood flow, and improving nerve conduction in patients with diabetic foot ulcers at six months after surgery.

摘要

目的

比较脊髓电刺激(SCS)与血管内再通治疗对糖尿病足溃疡的疗效。

材料与方法

回顾性分析符合纳入标准的 104 例糖尿病足溃疡患者,分为 SCS 治疗组(n=46)和血管内再通治疗组(n=46)。分析两组患者术前及术后 6 个月的生活质量评分(肝癌患者生命质量量表 2.0 版)、视觉模拟评分法(VAS)疼痛评分、下肢皮肤温度、下肢动脉超声结果及下肢肌电图结果,比较两种治疗方法对糖尿病足溃疡的疗效。

结果

92 例患者(男 73.9%,平均年龄 66.51±11.67 岁)完成术后 6 个月随访。SCS 治疗组患者的生活质量评分更高(25.54% vs 13.77%,p<0.05),疼痛评分下降更明显(69.18% vs 37.21%,p<0.05),下肢皮肤温度下降更明显(18.56% vs 7.24%,p<0.05)。术后 6 个月,SCS 治疗组患者下肢彩色多普勒动脉超声的血管扩张程度和神经传导速度均高于血管内再通治疗组(p<0.05)。

结论

SCS 治疗糖尿病足溃疡患者,术后 6 个月可明显改善患者的生活质量,缓解疼痛,提高下肢皮肤温度,增加下肢血流量,改善神经传导速度,其疗效优于血管内再通治疗。

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