Freeman L J, Conway A V, Nixon P G
J Psychosom Res. 1986;30(4):429-36. doi: 10.1016/0022-3999(86)90082-6.
The heart rate and electrocardiographic responses were documented in 40 subjects undergoing hyperventilation provocation tests. Forced overbreathing produced a similar mean heart rate increase in all subjects, regardless of whether the result of the provocation tests suggested the hyperventilation syndrome. In contrast subjects diagnosed as hyperventilators by virtue of prolonged hypocapnia in response to psychological provocation showed significant increased heart rate responses compared to the remaining subjects (p less than 0.001). Significant electrocardiographic abnormalities were also produced. The view is presented that the hypocapnia may allow persistence of the cardiovascular responses in the presence of emotional challenge.
对40名接受过度通气激发试验的受试者记录了心率和心电图反应。强制过度呼吸使所有受试者的平均心率有相似程度的增加，无论激发试验结果是否提示过度通气综合征。相比之下，因心理激发导致长时间低碳酸血症而被诊断为过度通气者的受试者，与其余受试者相比，心率反应显著增加（p<0.001）。还出现了显著的心电图异常。有人提出，低碳酸血症可能使心血管反应在存在情绪刺激时持续存在。
