Polesskiĭ V A, Kurdanov Kh A, Metel'skaia V A, Burlutskiĭ G I, Deev A D
Kardiologiia. 1986 Jul;26(7):42-5.
An assessment of one-feature and combined diagnostic value of plasma lipid and apolipoprotein parameters, using stepwise discriminant analysis, was designed to make possible correct differentiation between coronary heart disease (CHD) due to angiographically-verified coronary atherosclerosis and neurocirculatory dystonia (NCD) without signs of coronary arterial affection. The apolipoprotein B/apolipoprotein AI (apo B/apo AI) ratio was shown to be the best single apolipoprotein marker capable of correct differentiation between CHD and NCD in 74% of cases. It was similar to the best lipid diagnostic marker, the cholesterol atherogenic index, in terms of discriminating power. The combination of the apo B/apo AI ratio + age + systolic arterial blood pressure proved to be the best combined indicator, bringing the diagnostic error down to 18%.
采用逐步判别分析评估血浆脂质和载脂蛋白参数的单特征及联合诊断价值，旨在实现对经血管造影证实的冠状动脉粥样硬化所致冠心病（CHD）与无冠状动脉病变迹象的神经循环性肌张力障碍（NCD）进行正确鉴别。结果显示，载脂蛋白B/载脂蛋白AI（apo B/apo AI）比值是最佳的单个载脂蛋白标志物，在74%的病例中能够正确区分CHD和NCD。就鉴别能力而言，它与最佳脂质诊断标志物胆固醇致动脉粥样硬化指数相似。apo B/apo AI比值 + 年龄 + 收缩期动脉血压的组合被证明是最佳联合指标，可将诊断误差降至18%。
