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口腔内同时出现双重病理:一种不常见且具有诊断挑战性的表现。

Simultaneous presentation of dual pathologies within the oral cavity: an unusual and diagnostically challenging presentation.

机构信息

School of Dentistry, University of Birmingham, Birmingham, United Kingdom.

School of Dentistry, University of Birmingham, Birmingham, UK; Periodontal Research Group, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, United Kingdom.

出版信息

Br Dent J. 2023 Aug;235(4):250-254. doi: 10.1038/s41415-023-6138-5. Epub 2023 Aug 25.

Abstract

Necrotising sialometaplasia (NS) is a rare condition, with a limited scientific evidence base regarding its aetiology and pathophysiology. Diagnosing NS demands extensive investigatory tests. Their accuracy is vital in order to exclude oral malignancy and prevent unwarranted, invasive management.Within Birmingham Dental Hospital, a 22-year-old, South Asian woman presented with generalised pain from the lower right third molar extending to involve the palate, to which the patient's general medical practitioner previously attributed to a viral upper respiratory infection. Clinical examination revealed bilateral erythematous: non-ulcerated, palatal swellings (10 mm x 5 mm) at the greater palatine foramina. Following extensive investigations, the challenging definitive diagnoses of two distinct pathologies were made: non-ulcerative NS and pericoronitis.This case report describes the successful diagnosis and management of non-ulcerating NS, an 'atypical' presentation of a rare condition, that was confounded by a simultaneous episode of pericoronitis - a presentation not previously documented within scientific literature.

摘要

坏死性涎腺化生(NS)是一种罕见的疾病,其病因和病理生理学的科学证据有限。诊断 NS 需要广泛的检查。为了排除口腔恶性肿瘤并防止不必要的、侵入性的治疗,其准确性至关重要。在伯明翰牙科医院,一名 22 岁的南亚妇女出现了从右下第三磨牙延伸至腭部的全身性疼痛,之前她的全科医生将其归因于病毒性上呼吸道感染。临床检查显示双侧红斑:非溃疡性、腭肿胀(10 毫米 x 5 毫米)在更大的腭孔。经过广泛的调查,做出了两个截然不同的病理的具有挑战性的明确诊断:非溃疡性 NS 和冠周炎。本病例报告描述了非溃疡性 NS 的成功诊断和治疗,这是一种罕见疾病的“非典型”表现,同时并发了冠周炎,这种表现以前没有在科学文献中记录过。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71e0/10449619/93a4092a48f9/41415_2023_6138_Fig2_HTML.jpg

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