Chen David Z, Ganapathy Aravinda, Nayak Yash, Mejias Christopher, Bishop Grace L, Mellnick Vincent M, Ballard David H
School of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
School of Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
J Cardiovasc Dev Dis. 2023 Aug 14;10(8):347. doi: 10.3390/jcdd10080347.
Together, the Camper's and Scarpa's fasciae form the superficial fat layer of the abdominal wall. Though they have clinical and surgical relevance, little is known about their role in body composition across diverse patient populations. This study aimed to determine the relationship between patient characteristics, including sex and body mass index, and the distribution of Camper's and Scarpa's fascial layers in the abdominal wall. A total of 458 patients' abdominal CT examinations were segmented via CoreSlicer 1.0 to determine the surface area of each patient's Camper's, Scarpa's, and visceral fascia layers. The reproducibility of segmentation was corroborated by an inter-rater analysis of segmented data for 20 randomly chosen patients divided between three study investigators. Pearson correlation and Student's t-test analyses were performed to characterize the relationship between fascia distribution and demographic factors. The ratios of Camper's fascia, both as a proportion of superficial fat (r = -0.44 and < 0.0001) and as a proportion of total body fat (r = -0.34 and < 0.0001), showed statistically significant negative correlations with BMI. In contrast, the ratios of Scarpa's fascia, both as a proportion of superficial fat (r = 0.44 and < 0.0001) and as a proportion of total body fat (r = 0.41 and < 0.0001), exhibited statistically significant positive correlations with BMI. Between sexes, the females had a higher ratio of Scarpa's facia to total body fat compared to the males (36.9% vs. 31% and < 0.0001). The ICC values for the visceral fat, Scarpa fascia, and Camper fascia were 0.995, 0.991, and 0.995, respectively, which were all within the 'almost perfect' range (ICC = 0.81-1.00). These findings contribute novel insights by revealing that as BMI increases the proportion of Camper's fascia decreases, while the ratio of Scarpa's fascia increases. Such insights expand the scope of body composition studies, which typically focus solely on superficial and visceral fat ratios.
坎珀筋膜和斯卡帕筋膜共同构成腹壁的浅层脂肪层。尽管它们在临床和手术方面具有相关性，但对于它们在不同患者群体身体成分中的作用却知之甚少。本研究旨在确定包括性别和体重指数在内的患者特征与腹壁中坎珀筋膜和斯卡帕筋膜层分布之间的关系。通过CoreSlicer 1.0对458例患者的腹部CT检查进行分割，以确定每位患者的坎珀筋膜、斯卡帕筋膜和内脏筋膜层的表面积。通过对20名随机选择的患者（由三名研究人员进行分割）的分割数据进行评分者间分析，证实了分割的可重复性。进行了Pearson相关性分析和Student's t检验分析，以描述筋膜分布与人口统计学因素之间的关系。坎珀筋膜的比例，无论是作为浅层脂肪的比例（r = -0.44，P < 0.0001）还是作为全身脂肪的比例（r = -0.34，P < 0.0001），均与BMI呈统计学显著负相关。相比之下，斯卡帕筋膜的比例，无论是作为浅层脂肪的比例（r = 0.44，P < 0.0001）还是作为全身脂肪的比例（r = 0.41，P < 0.0001），均与BMI呈统计学显著正相关。在性别之间，女性斯卡帕筋膜与全身脂肪的比例高于男性（36.9%对31%，P < 0.0001）。内脏脂肪、斯卡帕筋膜和坎珀筋膜的组内相关系数（ICC）值分别为0.995、0.991和0.995，均在“几乎完美”范围内（ICC = 0.81 - 1.00）。这些发现揭示了随着BMI增加，坎珀筋膜的比例降低，而斯卡帕筋膜的比例增加，从而提供了新的见解。这些见解扩展了身体成分研究的范围，而身体成分研究通常仅关注浅层和内脏脂肪比例。
