Sick Johanna, König Daniel
Department of Sport Science, Centre for Sports Science and University Sports, University of Vienna, 1150 Vienna, Austria.
Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, University of Vienna, 1090 Vienna, Austria.
Healthcare (Basel). 2023 Aug 12;11(16):2277. doi: 10.3390/healthcare11162277.
Post COVID-19 Syndrome (PCS) is the persistence of symptoms after an infection with SARS-CoV-2 in both hospitalized and non-hospitalized COVID-19 survivors. Exercise was proposed as a rehabilitation measure for PCS and early studies focused on patients post-hospital discharge. The objective of this review is to summarize the results of trials investigating exercise interventions in non-hospitalized subjects with PCS and propose practical recommendations concerning safe exercise programming. A literature search in the databases MEDLINE and Scopus was conducted until 26 July 2023 and resulted in seven studies that met the criteria. In total, 935 subjects with PCS were investigated. Exercise enhanced aerobic fitness and physical function and relieved symptoms of dyspnea, fatigue and depression. Participants reported lower Post COVID-19 Functional Status scores post-intervention. The exercise programs were well tolerated with no adverse events. To ensure safety, medical examinations should take place in advance and there should be a regular evaluation of the individual responses to the training. Caution is advised when working with patients suffering from post-exertional malaise or diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome. There is a growing need for additional randomized controlled trials to investigate the effectiveness and safety of exercise in individuals with PCS.
新冠后综合征（PCS）是指感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）后，住院和非住院的新冠幸存者症状持续存在的情况。运动被提议作为PCS的一种康复措施，早期研究主要关注出院后的患者。本综述的目的是总结对非住院PCS患者进行运动干预的试验结果，并就安全的运动方案提出实用建议。截至2023年7月26日，在MEDLINE和Scopus数据库中进行了文献检索，共找到七项符合标准的研究。总共对935名PCS患者进行了调查。运动增强了有氧适能和身体功能，缓解了呼吸困难、疲劳和抑郁症状。参与者在干预后报告的新冠后功能状态评分较低。运动方案耐受性良好，无不良事件。为确保安全，应提前进行医学检查，并定期评估个体对训练的反应。对于患有运动后不适或被诊断为肌痛性脑脊髓炎/慢性疲劳综合征的患者，建议谨慎对待。越来越需要更多的随机对照试验来研究运动对PCS患者的有效性和安全性。
