Raus de Baviera Daniel, Ruiz-Canales Antonio, Barrajón-Catalán Enrique
Department of Engineering, Area of Agroforestry, Miguel Hernández University, 03312 Orihuela, Spain.
Institute for Research, Development and Innovation in Health Biotechnology, Miguel Hernández University, 03202 Elche, Spain.
Plants (Basel). 2023 Aug 18;12(16):2988. doi: 10.3390/plants12162988.
L. (Cistaceae) is a medicinal plant that has been used therapeutically since ancient times in the Mediterranean basin for its important pharmacological properties. The ability of to produce large quantities of a wide range of natural metabolites makes it an attractive source of raw material. The main constituents with bioactive functions that exert pharmacological effects are terpenes and polyphenols, with more than 200 identified compounds. The purpose of this review is to offer a detailed account of the botanical, ethnological, phytochemical, and pharmacological characteristics of with the aim of encouraging additional pharmaceutical investigations into the potential therapeutic benefits of this medicinal plant. This review was carried out using organized searches of the available literature up to July 2023. A detailed analysis of confirms its traditional use as a medicinal plant. The outcome of several studies suggests a deeper involvement of certain polyphenols and terpenes in multiple mechanisms such as inflammation and pain, with a potential application focus on neurodegenerative diseases and disorders. Other diseases such as prostate cancer and leukemia have already been researched with promising results for this plant, for which no intoxication has been reported in humans.
岩蔷薇属（半日花科）是一种药用植物，自古以来在地中海盆地因其重要的药理特性而被用于治疗。岩蔷薇属能够产生大量种类繁多的天然代谢产物，这使其成为一种有吸引力的原材料来源。发挥药理作用的具有生物活性功能的主要成分是萜类化合物和多酚类化合物，已鉴定出200多种化合物。本综述的目的是详细介绍岩蔷薇属的植物学、民族植物学、植物化学和药理学特征，以鼓励对这种药用植物的潜在治疗益处进行更多的药物研究。本综述通过对截至2023年7月的现有文献进行有组织的检索来开展。对岩蔷薇属的详细分析证实了其作为药用植物的传统用途。多项研究结果表明，某些多酚类化合物和萜类化合物在炎症和疼痛等多种机制中发挥着更深入的作用，潜在应用重点在于神经退行性疾病和病症。其他疾病，如前列腺癌和白血病，已经对这种植物进行了研究，并取得了有前景的结果，且尚未有关于该植物对人类产生中毒现象的报道。
