Department of Medicine, Section of Endocrinology, Diabetes, Nutrition & Weight Management, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.
Division of Endocrinology, Diabetes & Hypertension, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA.
Obes Surg. 2023 Oct;33(10):3127-3132. doi: 10.1007/s11695-023-06802-0. Epub 2023 Aug 26.
Micronutrient deficiencies are common complications after bariatric surgery as alterations to the gastrointestinal tract change absorption. Patients are recommended to take supplements including multivitamins, B complex, calcium, vitamin D, and iron after bariatric surgery, and can take these as specifically formulated vitamins for post-bariatric patients or separate vitamin supplements. We investigated the compliance, efficacy, and cost of specifically formulated vitamins for post-bariatric patients in comparison to separate vitamin supplements.
We surveyed 126 post-bariatric adult patients between February 1, 2022, and August 31, 2022, who had undergone bariatric surgery between 2014 and 2021 to assess the type of supplements taken, compliance, and cost. Demographics, type of bariatric surgery, and serum micronutrient levels were evaluated for all patients.
There were 51 patients taking formulated vitamins and 75 patients taking separate vitamins. The formulated vitamin group demonstrated greater adherence to optimal vitamin dosage (formulated vitamin group, 76.5% vs. separate supplement group, 30.7%; p < 0.001) and higher compliance (formulated vitamin group, 90.2% vs. separate supplement group, 66.7%; p = 0.002). The costs associated with both groups were comparable. No significant difference was observed in the incidence of micronutrient deficiency between the groups.
Our study shows that formulated vitamins do not offer significant difference in micronutrient levels or cost compared to separate standard vitamin supplements. However, formulated bariatric vitamins have improved compliance compared to separate vitamin supplements.
减重手术后常见的并发症是微量营养素缺乏，因为胃肠道的改变会影响吸收。建议减重手术后的患者补充多种维生素、B 族维生素、钙、维生素 D 和铁，可服用专为减重后患者定制的复合维生素或单独的维生素补充剂。我们研究了与单独的维生素补充剂相比，专门为减重后患者定制的复合维生素的依从性、疗效和成本。
我们调查了 126 名 2014 年至 2021 年间接受减重手术的成年减重后患者，评估他们所服用的补充剂类型、依从性和成本。对所有患者的人口统计学、减重手术类型和血清微量营养素水平进行了评估。
有 51 名患者服用配方维生素，75 名患者服用单独的维生素。配方维生素组更能坚持服用最佳维生素剂量（配方维生素组为 76.5%，单独补充剂组为 30.7%；p<0.001）和更高的依从性（配方维生素组为 90.2%，单独补充剂组为 66.7%；p=0.002）。两组的相关费用相当。两组间微量营养素缺乏的发生率无显著差异。
我们的研究表明，与单独的标准维生素补充剂相比，配方维生素在微量营养素水平或成本方面没有显著差异。然而，与单独的维生素补充剂相比，定制的减重复合维生素的依从性更高。
