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听力图正常的耳鸣患者维生素D缺乏的相关性

Association of Vitamin D Deficiency in Patients with Tinnitus with Normal Audiogram.

作者信息

Sharma Deepika, Gupta Vipan, Bhatia Shenny, Thakur Pooja

机构信息

Deptt of ENT, Maharishi Markendeshwar Medical College & Hospital, Kumarhatti solan, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):1992-1999. doi: 10.1007/s12070-023-03751-z. Epub 2023 Apr 24.

Abstract

In the present study we aim to evaluate serum vitamin D levels in participants having tinnitus with normal audiometric findings. Total 98 participants in the age range 20-70 year were included in the study. Participants underwent detail case history, ear examination, pure tone audiometry and impedance audiometry. 68 participants with subjective tinnitus for more than 3 months and with normal audiometric thresholds and "A" type tympanogram were included in study group and 30 participants without tinnitus in the control group. The participants fullfillng the inclusion criteria underwent thorough tinnitus evaluation which included administration of tinnitus severity index tinnitus handicap inventory, psychophysical evaluation of tinnitus (pitch matching, loudness matching) and assessment of Vitamin D levels. It was seen that the mean Vitamin D levels were significantly lower in study group, and out of 68 participants only 11 had optimal Vitamin D levels, 57 (83%) had Vitamin D levels less that 30 mg/dl. In the control group 20 (66%) had vitamin D deficiency. The difference came out to be statistically significant. Our study suggests that there is a link between vitamin D and tinnitus, in view of these findings we recommend evaluating serum Vitamin D levels in patients of chronic idiopathic tinnitus, especially in adults with normal hearing. Our study suggests vitamin D deficiency may be one of the risk factor for tinnitus in people with normal hearing in the absence of other manifestations.

摘要

在本研究中,我们旨在评估听力测验结果正常的耳鸣患者的血清维生素D水平。本研究共纳入98名年龄在20至70岁之间的参与者。参与者接受了详细的病史询问、耳部检查、纯音听力测定和声阻抗测听。研究组纳入了68名主观耳鸣超过3个月、听力阈值正常且鼓室图为“A”型的参与者,对照组纳入了30名无耳鸣的参与者。符合纳入标准的参与者接受了全面的耳鸣评估,包括耳鸣严重程度指数、耳鸣致残量表的评估、耳鸣的心理物理学评估(音调匹配、响度匹配)以及维生素D水平的评估。结果发现,研究组的平均维生素D水平显著较低,在68名参与者中,只有11人的维生素D水平处于最佳状态,57人(83%)的维生素D水平低于30mg/dl。对照组中有20人(66%)存在维生素D缺乏。差异具有统计学意义。我们的研究表明维生素D与耳鸣之间存在联系,鉴于这些发现,我们建议对慢性特发性耳鸣患者,尤其是听力正常的成年人,评估其血清维生素D水平。我们的研究表明,在没有其他表现的情况下,维生素D缺乏可能是听力正常人群耳鸣的危险因素之一。

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Association of Vitamin D Deficiency in Patients with Tinnitus with Normal Audiogram.听力图正常的耳鸣患者维生素D缺乏的相关性
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PLoS One. 2021 Aug 18;16(8):e0255482. doi: 10.1371/journal.pone.0255482. eCollection 2021.
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