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经皮内镜清创术治疗早期腰椎硬膜外脓肿的综合临床分析

A comprehensive clinical analysis of the use of percutaneous endoscopic debridement for the treatment of early lumbar epidural abscesses.

作者信息

Yang Yang, Li Jianhua, Chang Zhengqi

机构信息

Department of Orthopedics, 960th Hospital of PLA, Jinan, China.

出版信息

Front Surg. 2023 Aug 14;10:1215240. doi: 10.3389/fsurg.2023.1215240. eCollection 2023.

Abstract

OBJECTIVE

The purpose of this study is to evaluate the safety and efficacy of a percutaneous endoscopic debridement and drainage for lumbar infections with early epidural abscesses.

METHODS

Eight cases of early epidural abscess underwent lumbar intervertebral space debridement and drainage by percutaneous endoscopic. Laboratory indicators, pathogenic microorganisms and complications were documented, and the ASIA scores were used to assess preoperative and postoperative neurological function changes. Additionally, the VAS was used to evaluate the therapeutic effect.

RESULTS

The average duration of the drainage tube was 11.25 ± 3.96 days (7-20 days), and the epidural abscess was eliminated after the tube was taken out. Postoperative CRP (14.40 ± 12.50 mg/L) and ESR (48.37 ± 16.05 mm/1 h) were significantly lower than the preoperative CRP (62.5 ± 61.1 mg/L) and ESR (75.30 ± 26.20 mm/1 h). The VAS score after the operation (2.50 ± 0.92 points) was significantly lower than the one before the surgery (8.25 ± 0.83 points). 5 patients experienced lower extremity pain and neurological dysfunction prior to surgery, however, after drainage, the lower extremity pain dissipated and the lower extremity muscle strength improved in one patient. All 8 patients were followed up for a period of (28.13 ± 10.15) months, including 3 patients with spinal segmental instability who had lumbar bone graft and internal fixation for the second stage. At the end of the follow-up, all 8 patients were clinically cured without any progressive nerve injury, paraplegia or recurrence of infection.

CONCLUSION

Percutaneous Endoscopic Debridement and Drainage is an effective way to drain intraspinal abscesses, thus avoiding any potential progressive harm to the spinal cord.

摘要

目的

本研究旨在评估经皮内镜清创引流术治疗早期硬膜外脓肿所致腰椎感染的安全性和有效性。

方法

8例早期硬膜外脓肿患者接受了经皮内镜下腰椎间隙清创引流术。记录实验室指标、致病微生物及并发症情况,并采用美国脊髓损伤协会(ASIA)评分评估术前、术后神经功能变化。此外,采用视觉模拟评分法(VAS)评估治疗效果。

结果

引流管平均留置时间为11.25±3.96天(7 - 20天),拔管后硬膜外脓肿消失。术后C反应蛋白(CRP)(14.40±12.50mg/L)和血沉(ESR)(48.37±16.05mm/1h)显著低于术前CRP(62.5±61.1mg/L)和ESR(75.30±26.20mm/1h)。术后VAS评分(2.50±0.92分)显著低于术前(8.25±0.83分)。5例患者术前有下肢疼痛和神经功能障碍,引流后,1例患者下肢疼痛消失,下肢肌力改善。8例患者均随访了(28.13±10.15)个月,其中3例存在脊柱节段性不稳定的患者二期行腰椎植骨内固定术。随访结束时,8例患者均临床治愈,无任何进行性神经损伤、截瘫或感染复发。

结论

经皮内镜清创引流术是引流椎管内脓肿的有效方法,可避免对脊髓造成任何潜在的进行性损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e8a/10461046/b2e45e3fb236/fsurg-10-1215240-g001.jpg

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