Bahramnejad Mahdi, Dehnou Vahid Valipour, Eslami Rasoul
Department of Sports Sciences, Faculty of Literature & Human Sciences, Lorestan University, Khorramabad, IRAN.
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Allame Tabataba'i University, Tehran, IRAN.
Int J Exerc Sci. 2023 Aug 1;16(2):932-941. doi: 10.70252/QGYM2950. eCollection 2023.
Environmental enrichment (EE) is defined as a combination of complex inanimate and social stimulation. Physical activity and EE may augment the beneficial effects of each other. This study aimed to assess the effects of running in an enriched environment on neurotrophic factors in adult males. Twelve volunteer adult males (age 26.75 ± 5.34 yrs, body mass 70.72 ± 8.61 kg, height 172.50 ± 5.68 cm, VO 56.8 ± 2.93) completed two sessions, each consisted of one hour of running at an intensity of 12-13 on the Borg Scale. One session was completed in a normal environment, while the other was performed in an enriched environment (running track with several obstacles). Participants completed this randomized cross-over study interspersed by two weeks. Ten minutes before and after each session, blood samples were collected from all participants. Serum levels of BDNF, IGF-1, and VEGF were measured by ELISA. There was a statistically significant interaction of condition and exercise on BDNF, (1, 11) = 43.71, < 0.001, ; IGF-1, (1, 11) = 83.58, < 0.001, ; and VEGF, (1, 11) = 31.86, < 0.001, . There was also a significant effect of condition on BDNF (1, 11) = 21.08, = 0.001, ; IGF-1, (1, 11) = 32.35, < 0.001, ; and VEGF, (1, 11) = 116.29, < 0.001, . In addition, there was a significant effect of Exercise on BDNF (1, 11) = 52.86, < 0.001, ; IGF-1, (1, 11) = 39.14, < 0.001, ; and VEGF, (1, 11) = 171.21, < 0.001, . One hour of moderate-intensity running in adult males significantly increased serum levels of BDNF, IGF-1, and VEGF. But, exercising in an enriched environment may have a significantly greater effect. Therefore, if enhancing neurotrophic factors are desired outcomes of training sessions, then including obstacles may enhance the likelihood of achieving this goal.
环境富集（EE）被定义为复杂的无生命刺激和社会刺激的组合。身体活动和环境富集可能会增强彼此的有益效果。本研究旨在评估在富集环境中跑步对成年男性神经营养因子的影响。12名成年男性志愿者（年龄26.75±5.34岁，体重70.72±8.61千克，身高172.50±5.68厘米，VO₂ 56.8±2.93）完成了两个阶段，每个阶段包括在Borg量表上强度为12 - 13的一小时跑步。一个阶段在正常环境中完成，而另一个在富集环境（有几个障碍物的跑道）中进行。参与者完成了这项穿插两周的随机交叉研究。在每个阶段前后10分钟，从所有参与者身上采集血样。通过酶联免疫吸附测定法（ELISA）测量血清中脑源性神经营养因子（BDNF）、胰岛素样生长因子-1（IGF-1）和血管内皮生长因子（VEGF）的水平。条件和运动对BDNF存在统计学上显著的交互作用，F(1, 11) = 43.71，p < 0.001，η² = ；对IGF-1，F(1, 11) = 83.58，p < 0.001，η² = ；对VEGF，F(1, 11) = 31.86，p < 0.001，η² = 。条件对BDNF也有显著影响，F(1, 11) = 21.08，p = 0.001，η² = ；对IGF-1，F(1, 11) = 32.35，p < 0.001，η² = ；对VEGF，F(1, 11) = 116.29，p < 0.001，η² = 。此外，运动对BDNF有显著影响，F(1, 11) = 52.86，p < 0.001，η² = ；对IGF-1，F(1, 11) = 39.14，p < 0.001，η² = ；对VEGF，F(1, 11) = 171.21，p < 0.001，η² = 。成年男性进行一小时的中等强度跑步显著提高了血清中BDNF、IGF-1和VEGF的水平。但是，在富集环境中锻炼可能有显著更大的效果。因此，如果增强神经营养因子是训练课程期望的结果，那么设置障碍物可能会增加实现这一目标的可能性。
