[Changes in the intracellular glucose-6-phosphate dehydrogenase metabolism in the rat liver during thiamine deficiency].

Patterns of intracellular glucose-6-phosphate dehydrogenase turnover were studied in liver tissue of intact and thiamin-deficient rats using a new procedure for the enzyme purification. The alternations, found in the half-life period, in constant rates of synthesis and degradation of the key enzyme of the pentosephosphate pathway, correlated with a decrease of the glucose-6-phosphate dehydrogenase activity in vitamin B1 deficiency.