Elenkova A
Vutr Boles. 1986;25(3):103-8.
Cardiac output, plasma and blood volume were studied in 180 patients with essential hypertension via the method of dye dilution and neuro-hormonal studies were realized. In part of tha patients observed, the plasma renin activity and plasma aldosterone were established by radioimmune methods. The values of sodium in plasma and its excretion with urine were determines. Aldosterone and plasma sodium in the circulating blood volume were determined by methods, introduced by the author. Three subgroups of patients were differentiated on the base of the changes in sodium metabolism: with elevated sodium in plasma, with normal values of plasma sodium and with reduced sodium content in the circulating plasma volume. The changes in plasma sodium of the subgroups of patients with essential hypertension are accompanied by certain deviations in hemodynamics, in plasma aldosterone and in plasma renin activity.
通过染料稀释法对180例原发性高血压患者的心输出量、血浆和血容量进行了研究，并进行了神经激素研究。在部分观察的患者中，采用放射免疫法测定血浆肾素活性和血浆醛固酮。测定了血浆中钠的值及其尿排泄量。采用作者介绍的方法测定循环血容量中的醛固酮和血浆钠。根据钠代谢的变化将患者分为三个亚组：血浆钠升高组、血浆钠值正常组和循环血浆容量中钠含量降低组。原发性高血压患者亚组的血浆钠变化伴随着血流动力学、血浆醛固酮和血浆肾素活性的某些偏差。
