Zellbiologie, Universität Bayreuth, Bayreuth, Germany.
J Cell Biol. 2023 Oct 2;222(10). doi: 10.1083/jcb.202308119. Epub 2023 Sep 1.
It has long been an unresolved question whether the division machineries that assemble on the mitochondrial surface cooperate with factors inside the organelle. Now, two studies by Connor et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202303147) and Fukuda et al. (2023. Mol. Cell.https://doi.org/10.1016/j.molcel.2023.04.022) have identified an intermembrane space protein that is crucial for mitochondrial double membrane division.
长期以来，线粒体表面聚集的分裂机器是否与细胞器内的因子合作，一直是一个悬而未决的问题。现在，Connor 等人的两项研究（2023 年《细胞生物学杂志》，https://doi.org/10.1083/jcb.202303147）和 Fukuda 等人的两项研究（2023 年《分子细胞》，https://doi.org/10.1016/j.molcel.2023.04.022）已经鉴定出一种跨膜间隙蛋白，它对于线粒体双层膜分裂至关重要。
