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一种基于马尔可夫转移场和残差神经网络的心电图信号智能诊断方法。

An intelligent diagnostic method of ECG signal based on Markov transition field and a ResNet.

作者信息

Ji Lipeng, Wei Zhonghao, Hao Jian, Wang Chunli

机构信息

School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai, China.

School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai, China.

出版信息

Comput Methods Programs Biomed. 2023 Dec;242:107784. doi: 10.1016/j.cmpb.2023.107784. Epub 2023 Aug 30.

Abstract

BACKGROUND AND OBJECTIVE

Heart disease seriously threatens human life and health. It has the character of abruptness and is necessary to accurately monitor and intelligently diagnose electrocardiograph signals in real-time. As part of the automation of heart monitoring, the electrocardiogram (ECG) intelligent diagnosis method based on deep learning not only meets the needs of real-time and accurate but also can abandon relevant professional knowledge, which makes it possible to be promoted in the general population.

METHODS

This paper presents an intelligent diagnosis method based on a ResNet. Firstly, ECG signals from MIT-BIH Database are converted into 2-dim matrices by Markov Transition Field. Secondly, the matrices are used as the input of a ResNet. Then, the ResNet is able to extract high abstract features of various diseases and realize intelligent identification of five heartbeat types, including Normal Beat, Left Bundle Branch Block Beat, Right Bundle Branch Block Beat, Premature Ventricular Contraction Beat, and Atrial Premature Contraction Beat. Eventually, the proposed model is used to identify Normal Beat and Atrial Fibrillation(AF) based on the PAF Prediction Challenge Database(the PAFPC Database) to verify its generalization ability.

RESULTS

The experiment result shows that the intelligent diagnosis method can reach a high F1-score of 97.7% and a high accuracy upon to 99.2% on MIT-BIH Database, which are higher than the models proposed by other researchers. Its mean sensitivity and mean specificity are 97.42% and 99.54%, respectively. Moreover, the accuracy of the generalization ability verification experiment is 94.57% on the PAFPC Database, which is also higher than the results of other studies.

CONCLUSION

The research results show that the method proposed in this paper still achieves higher accuracy and higher F1-score than other methods without any data preprocessing. This method has better classification performance than traditional machine learning methods and other deep learning methods. That is, the method based on Markov Transition Field and a ResNet has good application prospects. At the same time, it has been verified that the model proposed in this paper also has excellent generalization ability.

摘要

背景与目的

心脏病严重威胁人类生命健康。其具有突发性,因此有必要对心电图信号进行实时准确监测和智能诊断。作为心脏监测自动化的一部分,基于深度学习的心电图(ECG)智能诊断方法不仅满足实时性和准确性需求,还可摒弃相关专业知识,使其在普通人群中得以推广。

方法

本文提出一种基于残差网络(ResNet)的智能诊断方法。首先,通过马尔可夫转移场将来自麻省理工学院 - 贝勒医学院(MIT - BIH)数据库的心电图信号转换为二维矩阵。其次,将这些矩阵作为ResNet的输入。然后,ResNet能够提取各种疾病的高抽象特征,并实现对五种心跳类型的智能识别,包括正常心跳、左束支传导阻滞心跳、右束支传导阻滞心跳、室性早搏心跳和房性早搏心跳。最终,基于阵发性房颤(PAF)预测挑战数据库(PAFPC数据库),使用所提出的模型来识别正常心跳和房颤,以验证其泛化能力。

结果

实验结果表明,该智能诊断方法在MIT - BIH数据库上可达到97.7%的高F1分数和高达99.2%的高精度,高于其他研究人员提出的模型。其平均灵敏度和平均特异性分别为97.42%和99.54%。此外,在PAFPC数据库上泛化能力验证实验的准确率为94.57%,也高于其他研究结果。

结论

研究结果表明,本文提出的方法在无需任何数据预处理的情况下,仍比其他方法实现了更高的准确率和更高的F1分数。该方法比传统机器学习方法和其他深度学习方法具有更好的分类性能。即基于马尔可夫转移场和ResNet的方法具有良好的应用前景。同时,已验证本文提出的模型也具有出色的泛化能力。

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