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匈牙利头颈部癌症患者的就诊延误及其临床意义。

Patient delay and its clinical significance among head and neck cancer patients in Hungary.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Department of Pathology, Forensic and Insurance Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

出版信息

Pathol Oncol Res. 2023 Aug 22;29:1611206. doi: 10.3389/pore.2023.1611206. eCollection 2023.

Abstract

Head and neck cancers represent a major health problem in Hungary. With their high incidence and mortality rates, Hungary is one of the world leaders in these indicators. The length of patient delay, defined as time from onset of symptoms to first medical consultation, is unknown in Hungarian patients with head and neck cancer. We aimed to use a representative sample of the Hungarian head and neck cancer patient population to determine patient delay according to disease localization and stage and to identify correlations with other clinical parameters. In our retrospective study, we reviewed patient documentation. For the inclusion, the patients had to be diagnosed with malignant tumors of the oral cavity, oropharynx, hypopharynx or larynx at the Department Head and Neck Surgery of Semmelweis University between 2012 and 2017. We identified 236 patients who met the inclusion criteria. The median delay was 9.5 weeks (range 0-209 weeks) and the mean delay of patients was 17.57 weeks (SD 23.67). There was a significant difference in patient delay data by location. Among glottic cancers, the most common diagnosis was an early stage (67%), compared with other localizations, including most commonly the oropharynx (81%) and hypopharynx (80%), where a locoregionally advanced stage was more frequent. Compared to data from different countries, the delay of Hungarian patients with head and neck cancer is significantly longer, which may contribute to the high mortality in Hungary. Screening and patient education in high-risk groups could contribute to earlier diagnosis and thus improve prognosis.

摘要

头颈部癌症是匈牙利的一个主要健康问题。由于其高发病率和死亡率,匈牙利在这些指标方面处于世界领先地位。匈牙利头颈部癌症患者的就诊延误时间(从症状出现到首次就诊的时间)尚不清楚。我们旨在使用匈牙利头颈部癌症患者人群的代表性样本,根据疾病定位和分期来确定就诊延误,并确定与其他临床参数的相关性。在我们的回顾性研究中,我们回顾了患者的病历。纳入标准为 2012 年至 2017 年间在塞梅尔维斯大学头颈外科被诊断为口腔、口咽、下咽或喉恶性肿瘤的患者。我们确定了 236 名符合纳入标准的患者。中位就诊延误时间为 9.5 周(范围 0-209 周),患者平均就诊延误时间为 17.57 周(SD 23.67)。就诊延误数据在定位上存在显著差异。在声门型癌症中,最常见的诊断为早期(67%),而其他部位,包括最常见的口咽(81%)和下咽(80%),局部区域进展期更为常见。与来自不同国家的数据相比,匈牙利头颈部癌症患者的就诊延误明显更长,这可能导致匈牙利的高死亡率。对高危人群进行筛查和患者教育可能有助于更早诊断,从而改善预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e7/10477355/dff068ef0d31/pore-29-1611206-g001.jpg

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