Shaikh Saeed A, Tahir Muhammad, Ahmed Nadeem
Dr. Saeed A Shaikh, FCPS. Department of Orthopaedics, Surgical Building, Jinnah Postgraduate Medical Centre, Rafiqui Shaheed Road, Karachi, Pakistan.
Mr. Muhammad Tahir, MRCSEng FCPS. Department of Orthopaedics, Surgical Building, Jinnah Postgraduate Medical Centre, Rafiqui Shaheed Road, Karachi, Pakistan.
Pak J Med Sci. 2023 Sep-Oct;39(5):1521-1525. doi: 10.12669/pjms.39.5.6521.
To compare the results of local administration of platelet-rich plasma (PRP) with methylprednisolone in the treatment of tennis elbow.
This retrospective cohort was conducted at Jinnah Postgraduate Medical Center (JPMC) during January 2017 to April 2018. Patients conservatively managed for lateral epicondylitis with local methylprednisolone injection or PRP injection were approached for possible inclusion in the study at 12 months of treatment. The primary outcome of the study was to determine the Numerical Pain Rating Score (NPRS) on resisted wrist extension. Whereas, the secondary outcomes were quick disability arm, shoulder, and hand score (qDASH), the grip strength and VAS for satisfaction. The baseline, six weeks and three month data on Grip strength, NPRS, and qDASH were extracted from the patients' medical records maintained at the hospital. The data were analyzed by using SPSS software.
A total of 91 patients were approached, of them 81 (89.01%) agreed to participate. There were 46 (56.79%) who received local methylprednisolone injection and 35 (43.20%) received PRP. At 12 months follow up, there was no difference in NPRS pain scores between the two groups (p=0.691); pain decreased in both groups at six weeks and at 12 months. There was no significant difference in the functional outcome (qDASH score) in both groups. Both groups were equally satisfied with the treatment they had received.
The study concluded that there is no difference between outcome and efficacy of both treatment modalities used for the treatment of tennis elbow in alleviating pain at 12 months.
比较局部注射富血小板血浆（PRP）与甲基强的松龙治疗网球肘的效果。
本回顾性队列研究于2017年1月至2018年4月在真纳研究生医学中心（JPMC）进行。对采用局部注射甲基强的松龙或PRP保守治疗外侧上髁炎的患者，在治疗12个月时邀请其参与本研究。本研究的主要结局是确定抗阻腕伸展时的数字疼痛评分（NPRS）。次要结局包括上肢、肩部和手部快速残疾评分（qDASH）、握力和满意度视觉模拟评分（VAS）。从医院保存的患者病历中提取握力、NPRS和qDASH的基线、六周和三个月数据。使用SPSS软件进行数据分析。
共邀请了91例患者，其中81例（89.01%）同意参与。46例（56.79%）接受了局部甲基强的松龙注射，35例（43.20%）接受了PRP注射。在12个月的随访中，两组的NPRS疼痛评分无差异（p=0.691）；两组在六周和12个月时疼痛均减轻。两组的功能结局（qDASH评分）无显著差异。两组对所接受的治疗同样满意。
该研究得出结论，在治疗网球肘时，两种治疗方式在12个月时缓解疼痛的结局和疗效无差异。
