Henan Comprehensive Utilization of Edible and Medicinal Plant Resources Engineering Technology Research Center, Zhengzhou Key Laboratory of Synthetic Biology of Natural Products, Huanghe Science and Technology College, Zhengzhou 450063, People's Republic of China.
Henan University, Kaifeng 475004, People's Republic of China.
J Agric Food Chem. 2023 Sep 20;71(37):13612-13632. doi: 10.1021/acs.jafc.3c04540. Epub 2023 Sep 8.
, a genus with more than 400 species, has a long history of use as an industrial bioreactor, biofertilizer, and biocontrol agent. It is considered a significant source of secondary metabolites (SMs) that possess unique structural features and a wide range of bioactivities. In recent years, numerous secondary metabolites of , including terpenoids, polyketides, peptides, alkaloids, and steroids, have been identified. Most of these SMs displayed antimicrobial, cytotoxic, and antifungal effects. This review focuses on the structural diversity, biological activities, and structure-activity relationships (SARs) of the SMs isolated from covered from 2018 to 2022. This study provides insights into the exploration and utilization of bioactive compounds from species in the agriculture or pharmaceutical industry.
, 一个拥有超过 400 种物种的属，有着作为工业生物反应器、生物肥料和生物防治剂的悠久历史。它被认为是具有独特结构特征和广泛生物活性的次生代谢产物 (SMs) 的重要来源。近年来，已经鉴定出 的许多次生代谢产物，包括萜类、聚酮类、肽类、生物碱和甾体类。这些 SMs 大多数具有抗菌、细胞毒性和抗真菌作用。本综述重点介绍了 2018 年至 2022 年期间从 中分离得到的次生代谢产物的结构多样性、生物活性和构效关系 (SARs)。本研究为农业或制药行业中探索和利用 物种的生物活性化合物提供了思路。
