综合膳食抗氧化指数与糖尿病患病率呈负相关，且独立于心血管疾病。
Composite dietary antioxidant index was negatively associated with the prevalence of diabetes independent of cardiovascular diseases.
作者信息
Chen Xiaojie, Lu He, Chen Yingwei, Sang Haiqiang, Tang Yi, Zhao Yifan
机构信息
Department Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Cardiology, The People's Hospital of Jiawang District of Xuzhou, XuZhou, China.
出版信息
Diabetol Metab Syndr. 2023 Sep 8;15(1):183. doi: 10.1186/s13098-023-01150-6.
AIM
The association between composite dietary antioxidant index (CDAI) and diabetes remains unknown. Our study was to investigate the association of CDAI with diabetes.
METHODS
A total of 11,956 participants were enrolled from the National Health and Nutrition Examination Surveys (NHANES). The CDAI was calculated from the intake of six dietary antioxidants. Multivariable logistic regressions were performed to explore the associations between CDAI and the prevalence of diabetes and glycemic index. Non-linear associations were explored using restricted cubic splines.
RESULTS
In the multivariate logistic regression model, the odds ratio (95% confidence interval) of CDAI associating with obesity was 0.98 (0.97-1.00; p = 0.033). Compared with the lowest quartile, the highest quartile was related to 0.84-fold risk of diabetes (0.71-0.99; p = 0.035). However, CDAI was not independently associated with fasting glucose and hemoglobin A1c.
CONCLUSION
CDAI was negatively associated with diabetes and the relationship was independent of other traditional risk factors.
目的
复合膳食抗氧化指数（CDAI）与糖尿病之间的关联尚不清楚。我们的研究旨在调查CDAI与糖尿病的关联。
方法
从国家健康与营养检查调查（NHANES）中招募了总共11956名参与者。CDAI由六种膳食抗氧化剂的摄入量计算得出。进行多变量逻辑回归以探讨CDAI与糖尿病患病率和血糖指数之间的关联。使用受限立方样条探索非线性关联。
结果
在多变量逻辑回归模型中，CDAI与肥胖相关的比值比（95%置信区间）为0.98（0.97 - 1.00；p = 0.033）。与最低四分位数相比，最高四分位数与糖尿病风险的0.84倍相关（0.71 - 0.99；p = 0.035）。然而，CDAI与空腹血糖和糖化血红蛋白无独立关联。
结论
CDAI与糖尿病呈负相关，且这种关系独立于其他传统风险因素。
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