Faculty of Dentistry, Wroclaw Medical University, 50-425 Wrocław, Poland.
Student Scientific Group of Adult Allergology, Wroclaw Medical University, 50-369 Wrocław, Poland.
Nutrients. 2023 Aug 31;15(17):3813. doi: 10.3390/nu15173813.
Obesity is a global problem. It affects every age group and is associated with many negative health effects. As an example, there is a relationship between obesity and allergic and immunological diseases, such as asthma, psoriasis, food allergies, allergic rhinitis and atopic dermatitis. Obesity undeniably affects their development. In addition, it causes adverse changes in the course and response to therapy in relation to patients without excessive body weight. The treatment of diseases associated with obesity is difficult; drugs are less effective and must be used in higher doses, and their use in patients with obesity is often associated with higher risks. The main form of treatment of all obesity-related diseases is a change in eating habits and increased physical activity, which leads to a decrease in body fat mass. The positive effect of reducing BMI has been confirmed in many independent studies. This paper reviews various types of research documents published since 2019. It aims to systematize the latest knowledge and highlight the need for further research for effective and sustainable treatment options for obesity, its complications and obesity-related diseases.
肥胖是一个全球性问题。它影响着各个年龄段的人群，与许多负面健康影响有关。例如，肥胖与过敏和免疫性疾病之间存在关联，如哮喘、银屑病、食物过敏、过敏性鼻炎和特应性皮炎。肥胖无疑会影响这些疾病的发展。此外，它还会导致肥胖患者在治疗过程和治疗反应方面发生不良变化，而这些变化在体重正常的患者中并不常见。与肥胖相关疾病的治疗较为困难；药物的疗效较低，必须使用更高的剂量，而在肥胖患者中使用这些药物往往伴随着更高的风险。所有与肥胖相关疾病的主要治疗形式都是改变饮食习惯和增加身体活动，从而减少体脂量。许多独立研究已经证实降低 BMI 可带来积极效果。本文回顾了自 2019 年以来发表的各种类型的研究文献，旨在对最新知识进行系统化，并强调需要进一步研究以找到针对肥胖、肥胖相关并发症和肥胖相关疾病的有效和可持续治疗方法。
