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埃及骨健康学会:埃及骨质疏松性髋部骨折人群的发生率和地域特征。

Incidence and geographic characteristics of the population with osteoporotic hip fracture in Egypt- by the Egyptian Academy of Bone Health.

机构信息

Canterbury Christ Church University, England, UK.

Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt.

出版信息

Arch Osteoporos. 2023 Sep 9;18(1):115. doi: 10.1007/s11657-023-01325-8.

Abstract

UNLABELLED

This work studies the epidemiology of hip fracture in Egypt. While the incidence of hip fracture in Egypt matches that of the Mediterranean region, there was geographic variation in osteoporotic hip fracture incidence between the north and south of Egypt.

PURPOSE

To assess the incidence of hip fracture in Egypt, with special emphasis on the geographic and demographic variation among the Egyptian population.

METHODS

The incidence of hip fractures treated in two Egyptian FLS centers was calculated for the period of February 2022-February 2023. Demographic information was recorded for every patient on the national register. All patients completed a baseline questionnaire, had clinical evaluation, fracture risk, falls, and sarcopenia risk assessment. A DXA scan was carried out for every patient.

RESULTS

The annual incidence of low-energy hip fracture in individuals aged 40 years or more in Egypt in 2022-2023 was 123.34 per 100,000 in women and 55.19 per 100,000 in men. The incidence of hip fractures was higher in south Egypt (113.62) versus north Egypt (64.8). This was consistent for both genders. Bone mineral density was significantly (p < 0.01) lower in south Egypt at both the spine, distal forearm, as well as hip trochanters, whereas there was no significant difference between both locations in terms of the total hip and neck of the femur. Yet, falls risk, sarcopenia, as well as functional disability rates were significantly (p < 0.001) higher in the north.

CONCLUSION

In Egypt, the hip fracture incidence was higher in the south compared to the north. Several modifiable factors contribute to fragility fracture risk independent of BMD, creating complex interrelationships between BMD, risk factors, and fracture risk.

摘要

目的

评估埃及髋部骨折的发病率,特别关注埃及人口的地理和人口统计学差异。

方法

计算了 2022 年 2 月至 2023 年 2 月期间在埃及 2 个 FLS 中心治疗的髋部骨折的发病率。每位患者的人口统计学信息均在国家登记册上记录。所有患者均完成基线问卷,进行临床评估、骨折风险、跌倒和肌肉减少症风险评估。对每位患者进行 DXA 扫描。

结果

2022-2023 年,埃及 40 岁及以上人群中,女性低能量髋部骨折的年发病率为每 10 万人 123.34 例,男性为每 10 万人 55.19 例。埃及南部(113.62)髋部骨折的发病率高于北部(64.8)。这在两性中都是一致的。无论是在脊柱、远端前臂还是髋部转子,南部的骨密度都明显(p<0.01)低于北部,而在全髋和股骨颈方面,两个地区之间没有显著差异。然而,北部的跌倒风险、肌肉减少症和功能障碍率明显(p<0.001)更高。

结论

在埃及,南部髋部骨折的发病率高于北部。一些可改变的因素独立于 BMD 增加脆性骨折风险,在 BMD、危险因素和骨折风险之间产生复杂的相互关系。

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