母体接种 COVID-19 疫苗后的 Delta 变异株中和抗体反应。
Delta variant neutralizing antibody response following maternal COVID-19 vaccination.
机构信息
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Duke University, Durham, NC.
Duke Human Vaccine Institute, Duke University, Durham, NC.
出版信息
Am J Infect Control. 2024 Feb;52(2):252-254. doi: 10.1016/j.ajic.2023.09.002. Epub 2023 Sep 7.
The Delta pandemic wave saw increased maternal morbidity and mortality compared to prior viral strains. COVID-19 vaccination in pregnancy elicits detectable levels of neutralizing antibodies to SARS-CoV-2 wild type and SARS-CoV-2 Delta variants in both maternal and neonatal samples at delivery. Our results demonstrate the effectiveness of vaccination which confers an immunological response against newer, and potentially more dangerous, viral variants.
与先前的病毒株相比，德尔塔疫情期间产妇发病率和死亡率上升。在妊娠期间接种 COVID-19 疫苗可在分娩时的母本和新生儿样本中诱导出针对 SARS-CoV-2 野生型和 SARS-CoV-2 德尔塔变异株的可检测水平的中和抗体。我们的研究结果表明了疫苗接种的有效性，疫苗接种可针对新型且可能更危险的病毒变异株产生免疫应答。
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