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Commentary: Copper and cuproptosis-related genes in hepatocellular carcinoma: therapeutic biomarkers targeting tumor immune microenvironment and immune checkpoints.

作者信息

Xu Fangshi, Cai Danrui, Yang Zheng, Yin Jian, Sun Yi

机构信息

Department of Urology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.

Department of Ophthalmology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

出版信息

Front Immunol. 2023 Aug 25;14:1265565. doi: 10.3389/fimmu.2023.1265565. eCollection 2023.

DOI:10.3389/fimmu.2023.1265565
PMID:37691933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10485830/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e82/10485830/179e28530800/fimmu-14-1265565-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e82/10485830/179e28530800/fimmu-14-1265565-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e82/10485830/179e28530800/fimmu-14-1265565-g001.jpg

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Commentary: Copper and cuproptosis-related genes in hepatocellular carcinoma: therapeutic biomarkers targeting tumor immune microenvironment and immune checkpoints.述评:肝细胞癌中的铜与铜死亡相关基因:靶向肿瘤免疫微环境和免疫检查点的治疗生物标志物
Front Immunol. 2023 Aug 25;14:1265565. doi: 10.3389/fimmu.2023.1265565. eCollection 2023.
2
Copper and cuproptosis-related genes in hepatocellular carcinoma: therapeutic biomarkers targeting tumor immune microenvironment and immune checkpoints.肝细胞癌中的铜和铜死亡相关基因:针对肿瘤免疫微环境和免疫检查点的治疗性生物标志物。
Front Immunol. 2023 Apr 20;14:1123231. doi: 10.3389/fimmu.2023.1123231. eCollection 2023.
3
Signature construction and molecular subtype identification based on cuproptosis-related genes to predict the prognosis and immune activity of patients with hepatocellular carcinoma.基于铜死亡相关基因的signature 构建和分子亚型鉴定,预测肝细胞癌患者的预后和免疫活性。
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Cuproptosis regulatory genes greatly contribute to clinical assessments of hepatocellular carcinoma.铜死亡调控基因极大地促进了肝细胞癌的临床评估。
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Identification of copper metabolism and cuproptosis-related subtypes for predicting prognosis tumor microenvironment and drug candidates in hepatocellular carcinoma.鉴定铜代谢和铜死亡相关亚型,以预测肝细胞癌的预后、肿瘤微环境和药物靶点。
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本文引用的文献

1
Identification and validation of a novel cuproptosis-related stemness signature to predict prognosis and immune landscape in lung adenocarcinoma by integrating single-cell and bulk RNA-sequencing.通过整合单细胞和批量 RNA 测序,鉴定和验证一种新的铜死亡相关干性特征,以预测肺腺癌的预后和免疫图谱。
Front Immunol. 2023 May 23;14:1174762. doi: 10.3389/fimmu.2023.1174762. eCollection 2023.
2
The cuproptosis-associated 11 gene signature as a predictor for outcomes and response to Bacillus Calmette-Guerin and immune checkpoint inhibitor therapies in bladder carcinoma.铜死亡相关的 11 基因特征作为膀胱癌患者对卡介苗和免疫检查点抑制剂治疗反应和结局的预测因子。
Front Immunol. 2023 May 3;14:1126247. doi: 10.3389/fimmu.2023.1126247. eCollection 2023.
3
Copper and cuproptosis-related genes in hepatocellular carcinoma: therapeutic biomarkers targeting tumor immune microenvironment and immune checkpoints.肝细胞癌中的铜和铜死亡相关基因:针对肿瘤免疫微环境和免疫检查点的治疗性生物标志物。
Front Immunol. 2023 Apr 20;14:1123231. doi: 10.3389/fimmu.2023.1123231. eCollection 2023.
4
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022.2012年至2022年癌症中铁死亡、坏死性凋亡、焦亡和铜死亡的文献计量分析
Cell Death Discov. 2023 Apr 15;9(1):129. doi: 10.1038/s41420-023-01421-1.
5
Cuproptosis: mechanisms and links with cancers.铜死亡:机制与癌症的关联。
Mol Cancer. 2023 Mar 7;22(1):46. doi: 10.1186/s12943-023-01732-y.
6
Bioinformatics analysis and experimental validation of cuproptosis-related lncRNA LINC02154 in clear cell renal cell carcinoma.生物信息学分析和实验验证在透明细胞肾细胞癌中铜死亡相关 lncRNA LINC02154 的作用。
BMC Cancer. 2023 Feb 16;23(1):160. doi: 10.1186/s12885-023-10639-2.
7
Construction and systematic evaluation of a machine learning-based cuproptosis-related lncRNA score signature to predict the response to immunotherapy in hepatocellular carcinoma.基于机器学习的铜死亡相关 lncRNA 评分模型的构建及其在预测肝细胞癌免疫治疗反应中的系统评价。
Front Immunol. 2023 Jan 25;14:1097075. doi: 10.3389/fimmu.2023.1097075. eCollection 2023.
8
The role of cuproptosis-related gene in the classification and prognosis of melanoma.铜死亡相关基因在黑色素瘤分类和预后中的作用。
Front Immunol. 2022 Oct 19;13:986214. doi: 10.3389/fimmu.2022.986214. eCollection 2022.
9
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications.铁死亡研究十周年:新兴机制、生理功能与治疗应用
Cell. 2022 Jul 7;185(14):2401-2421. doi: 10.1016/j.cell.2022.06.003.
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Sci China Life Sci. 2022 Oct;65(10):2017-2030. doi: 10.1007/s11427-021-2048-2. Epub 2022 Mar 25.