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结节病与淋巴瘤:一位广泛淋巴结肿大患者的临床诊断困境

Sarcoidosis Versus Lymphoma: A Clinical Diagnostic Dilemma in a Patient With Extensive Lymphadenopathy.

作者信息

Ji Beisi, Khatun Nazima, Mostafidi Elmira, Gupta Raavi, McFarlane Samy I

机构信息

Internal Medicine, Downstate-Health Sciences University of New York, Downstate Medical Center, Brooklyn, USA.

Pathology, Downstate-Health Sciences University of New York, Downstate Medical Center, Brooklyn, USA.

出版信息

Cureus. 2023 Aug 10;15(8):e43281. doi: 10.7759/cureus.43281. eCollection 2023 Aug.

DOI:10.7759/cureus.43281
PMID:37692669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10492610/
Abstract

Sarcoidosis is a granulomatous disease involving multiple organ systems. In its classic form, sarcoidosis is associated with non-caseating granuloma. Several differential diagnostic entities exist for sarcoidosis, including tuberculosis (TB), as well as lymphomas. In this report, we present a case of sarcoidosis in a 55-year-old male with diffuse lymphadenopathy and hepatosplenic involvement, highlighting the differential diagnostic point for this disease.

摘要

结节病是一种累及多个器官系统的肉芽肿性疾病。在其典型形式中,结节病与非干酪样肉芽肿相关。结节病存在几种鉴别诊断实体,包括结核病(TB)以及淋巴瘤。在本报告中,我们呈现了一例55岁男性结节病病例,该患者有弥漫性淋巴结病和肝脾受累,突出了这种疾病的鉴别诊断要点。

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本文引用的文献

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Diffuse Sarcoidosis Masquerading as Widespread Malignant Disease: A Rare Case Report and Literature Review.弥漫性肉样瘤病伪装为广泛恶性疾病:一例罕见病例报告及文献复习。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620938942. doi: 10.1177/2324709620938942.
2
Mnemonic for the differential diagnosis of non-caseating granulomas.非干酪样肉芽肿鉴别诊断的记忆方法。
Sarcoidosis Vasc Diffuse Lung Dis. 2017;34(2):200-207. doi: 10.36141/svdld.v34i2.5674. Epub 2017 Apr 28.
3
Granuloma With an Underlying Lymphoma: A Diagnostic Challenge and a Wider Histologic Spectrum Including Adult T-Cell Leukemia/Lymphoma.
J Pers Med. 2024 Jan 23;14(2):134. doi: 10.3390/jpm14020134.
伴有潜在淋巴瘤的肉芽肿:诊断挑战和更广泛的组织学谱,包括成人 T 细胞白血病/淋巴瘤。
Appl Immunohistochem Mol Morphol. 2020 Apr;28(4):316-324. doi: 10.1097/PAI.0000000000000731.
4
Clinical presentation and characteristics of lymphoma in the head and neck region.头颈部淋巴瘤的临床表现和特征。
Head Face Med. 2019 Jan 3;15(1):1. doi: 10.1186/s13005-018-0186-0.
5
A patient presenting with generalised lympadenopathy--sarcoidosis, lymphoma or tuberculosis?一名出现全身淋巴结病的患者——结节病、淋巴瘤还是结核病?
BMJ Case Rep. 2012 Feb 25;2012:bcr1120115150. doi: 10.1136/bcr.11.2011.5150.
6
M. tuberculosis in Lymph Node Biopsy Paraffin-Embedded Sections.淋巴结活检石蜡包埋切片中的结核分枝杆菌
Tuberc Res Treat. 2011;2011:127817. doi: 10.1155/2011/127817. Epub 2011 Dec 13.
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Extranodal non-Hodgkin's lymphoma presenting as gingival mass.表现为牙龈肿物的结外非霍奇金淋巴瘤
J Indian Soc Periodontol. 2011 Oct;15(4):418-20. doi: 10.4103/0972-124X.92584.
8
Sarcoidosis and lymphoma: case series and literature review.结节病与淋巴瘤:病例系列及文献综述
Sarcoidosis Vasc Diffuse Lung Dis. 2011 Oct;28(2):146-52.
9
Stage IV sarcoidosis: comparison of survival with the general population and causes of death.IV 期结节病:与普通人群的生存比较和死亡原因。
Eur Respir J. 2011 Dec;38(6):1368-73. doi: 10.1183/09031936.00187410. Epub 2011 Nov 10.
10
Pulmonary sarcoidosis.肺结节病
Semin Respir Crit Care Med. 2007 Feb;28(1):53-74. doi: 10.1055/s-2007-970333.