Bhalla Ashu S, Das A, Naranje P, Goyal A, Guleria R, Khilnani Gopi C
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
Indian J Radiol Imaging. 2017 Oct-Dec;27(4):369-379. doi: 10.4103/ijri.IJRI_200_17.
Sarcoidosis is a multi-systemic disorder of unknown etiology, although commonly believed to be immune-mediated. Histologically, it is characterized by noncaseating granuloma which contrasts against the caseating granuloma seen in tuberculosis (TB), an infectious disease that closely mimics sarcoidosis, both clinically as well as radiologically. In TB-endemic regions, the overlapping clinico-radiological manifestations create significant diagnostic dilemma, especially since the management options are markedly different in the two entities. Part 1 of this review aims to summarize the clinical, laboratory, and imaging features of sarcoidosis, encompassing both typical and atypical manifestations, in an attempt to distinguish between the two disease entities.
结节病是一种病因不明的多系统疾病，尽管通常认为是免疫介导的。从组织学上看，其特征是非干酪样肉芽肿，这与结核病（TB）中所见的干酪样肉芽肿形成对比，结核病是一种在临床和放射学上都与结节病极为相似的传染病。在结核病流行地区，临床和放射学表现的重叠造成了重大的诊断困境，特别是因为这两种疾病的治疗选择明显不同。本综述的第一部分旨在总结结节病的临床、实验室和影像学特征，包括典型和非典型表现，以试图区分这两种疾病。
