Abdul Nishath Sayed, AlGhannam Sara Mohammed, Almughaiseeb Atheer Abdulaziz, Bindawoad Faisal Ahmed, Alduraibi Sara Mohammed, Shenoy Mahesh
Faculty of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Riyadh Elm University, Riyadh, KSA.
MOH, Prince Saud Bin Jalawi hospital, Alahsa, KSA.
Bioinformation. 2022 Oct 31;18(10):1021-1028. doi: 10.6026/973206300181021. eCollection 2022.
Salivary secretions possess a number of biomarkers beneficial for the diagnosis of a plethora of oral and other systemic disorders. Therefore, it is of interest to analyse and discuss the significance of saliva and its constituents as a valuable tool in aiding diagnostics in clinical settings by reviewing available literature and controlled trials. Using the PRISMA framework, a thorough review of research that were listed in the PubMed, Web of Science, and Cochrane library databases was performed which revealed 212 papers, 54 of which were thoroughly evaluated. Exclusion and inclusion criteria were used to choose studies that were applicable for the review. The selected studies reported a number of diseases that were diagnosed using salivary constituents in the same way as other methods of diagnosis, with a number of benefits. Thus, data shows that saliva is an excellent source for biomarkers which can be used for furthering medical diagnosis like other diagnostic procedures.
唾液分泌物含有许多生物标志物,有助于诊断多种口腔疾病和其他全身性疾病。因此,通过回顾现有文献和对照试验,分析和讨论唾液及其成分作为临床诊断辅助的宝贵工具的意义具有重要意义。使用PRISMA框架,对PubMed、科学网和Cochrane图书馆数据库中列出的研究进行了全面回顾,共检索到212篇论文,其中54篇进行了深入评估。采用排除和纳入标准来选择适用于该综述的研究。所选研究报告了一些疾病,这些疾病使用唾液成分进行诊断的方式与其他诊断方法相同,且具有诸多益处。因此,数据表明唾液是生物标志物的极佳来源,可像其他诊断程序一样用于推进医学诊断。