Ayano Getinet, Tsegay Light, Gizachew Yitbarek, Necho Mogesie, Yohannes Kalkidan, Abraha Mebratu, Demelash Sileshi, Anbesaw Tamrat, Alati Rosa
School of Population Health, Curtin University, WA, Australia.
Aksum University, Aksum, Ethiopia.
Psychiatry Res. 2023 Oct;328:115449. doi: 10.1016/j.psychres.2023.115449. Epub 2023 Sep 9.
Attention deficit hyperactivity disorder (ADHD) is a class of neurodevelopmental disorders which is commonly diagnosed in school-age children, but it can occur in any age group. To provide a robust synthesis of published evidence on the prevalence of ADHD in adults, we conducted an umbrella review of systematic reviews and meta-analyses.
The review was guided by preferred reporting items for systematic review and meta-analysis (PRISMA). We searched PsychINFO, Web of Science, PubMed, and Scopus to retrieve pertinent studies. The review protocol was registered with PROSPERO (CRD42023389704). A Measurement Tool to Assess Systematic Reviews (AMSTAR) was used to assess the quality of the included studies. A random-effects model was used to perform a meta-analysis.
Five systematic reviews and meta-analyses (57 unique primary studies) with data on 21,142,129 adult participants were eligible for inclusion in this umbrella review. Inverse variance weighted random effect meta-analysis of these studies indicated that the pooled prevalence of ADHD in adults was 3.10% (95%CI 2.60-3.60%). ADHD-I (the inattentive type of ADHD) remained the commonest type of ADHD, followed by ADHD-HI (the hyperactive type) and ADHD-C (the combined type).
The results indicate that ADHD is relatively high in adults, with ADHD-I remaining the most common subtype. Attention should be given to preventing, reducing, identifying, and managing ADHD in adults.
注意力缺陷多动障碍（ADHD）是一类神经发育障碍，通常在学龄儿童中被诊断出来，但也可能发生在任何年龄组。为了对已发表的关于成人ADHD患病率的证据进行有力的综合分析，我们对系统评价和荟萃分析进行了一项伞状综述。
该综述以系统评价和荟萃分析的首选报告项目（PRISMA）为指导。我们检索了PsychINFO、科学网、PubMed和Scopus以检索相关研究。该综述方案已在PROSPERO（CRD42023389704）注册。使用系统评价评估测量工具（AMSTAR）来评估纳入研究的质量。采用随机效应模型进行荟萃分析。
五项系统评价和荟萃分析（57项独特的原始研究）提供了21,142,129名成年参与者的数据，符合纳入本伞状综述的条件。对这些研究进行的逆方差加权随机效应荟萃分析表明，成人ADHD的合并患病率为3.10%（95%CI 2.60-3.60%）。注意缺陷型ADHD（ADHD-I）仍然是最常见的ADHD类型，其次是多动型ADHD（ADHD-HI）和混合型ADHD（ADHD-C）。
结果表明，ADHD在成人中的患病率相对较高，ADHD-I仍然是最常见的亚型。应重视成人ADHD的预防、减少、识别和管理。
