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尿中苯硫酸酯和苯葡萄糖醛酸酯作为苯酚暴露指标的意义。

Significance of urinary phenyl sulfate and phenyl glucuronide as indices of exposure to phenol.

作者信息

Ogata M, Yamasaki Y, Kawai T

出版信息

Int Arch Occup Environ Health. 1986;58(3):197-202. doi: 10.1007/BF00432101.

DOI:10.1007/BF00432101
PMID:3770959
Abstract

Urine samples from subjects, who had been using phenol for treatment of chemical fiber in factories, were analysed for urinary phenyl sulfate (PhS) and phenyl glucuronide (PhG) by high-performance liquid chromatography (HPLC). The urinary levels of phenol metabolites (PhG and PhS) had a significant correlation with the environmental concentration of phenol. The urinary concentration of phenol metabolites, as a total of PhS and PhG, corresponding to 5 ppm of environmental phenol was 251 mg phenol/g creatinine.

摘要

对曾在工厂使用苯酚处理化学纤维的受试者的尿液样本，采用高效液相色谱法（HPLC）分析尿中苯硫酸酯（PhS）和苯葡萄糖醛酸苷（PhG）。苯酚代谢物（PhG和PhS）的尿中水平与环境中苯酚浓度存在显著相关性。环境苯酚浓度为5 ppm时，作为PhS和PhG总和的苯酚代谢物尿浓度为251 mg苯酚/克肌酐。

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Int Arch Occup Environ Health. 1986;58(3):197-202. doi: 10.1007/BF00432101.
2
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3
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本文引用的文献

1
URINARY EXCRETION OF PHENOL BY MEN EXPOSED TO VAPOUR OF BENZENE: A SCREENING TEST.接触苯蒸气的男性尿中酚的排泄：一项筛查试验。
Br J Ind Med. 1965 Jan;22(1):21-6. doi: 10.1136/oem.22.1.21.
2
Studies in detoxication. 54. The metabolism of benzene. (a) The formation of phenylglucuronide and phenylsulphuric acid from [14C]benzene. (b) The metabolism of [14C]phenol.解毒研究。54. 苯的代谢。(a) 由[14C]苯形成苯基葡萄糖醛酸苷和苯硫酸。(b) [14C]苯酚的代谢。
Biochem J. 1953 Sep;55(2):337-40. doi: 10.1042/bj0550337.
3
Creatinine in urine as an index of urinary excretion rate.
通过自动高效液相色谱法同时测定尿液中的肌酐以及甲苯、二甲苯、苯乙烯、乙苯和苯酚的代谢物。
Int Arch Occup Environ Health. 1988;61(1-2):131-40. doi: 10.1007/BF00381617.
尿肌酐作为尿排泄率的指标。
Health Phys. 1966 Jun;12(6):843-50. doi: 10.1097/00004032-196606000-00014.
4
Evaluation of exposure to phenol: absorption of phenol vapour in the lungs and through the skin and excretion of phenol in urine.苯酚暴露评估：苯酚蒸气在肺部的吸收、经皮肤的吸收以及苯酚在尿液中的排泄。
Br J Ind Med. 1971 Apr;28(2):172-8. doi: 10.1136/oem.28.2.172.
5
Urinary excretion of hippuric acid and m- or p-methylhippuric acid in the urine of persons exposed to vapours of toluene and m- or p-xylene as a test of exposure.测定接触甲苯及间二甲苯或对二甲苯蒸气人员尿液中马尿酸、间甲基马尿酸或对甲基马尿酸的排泄量，以此作为接触检测指标。
Br J Ind Med. 1970 Jan;27(1):43-50. doi: 10.1136/oem.27.1.43.
6
Quantitative relationship between atmospheric phenol vapour and phenol in the urine of workers in Bakelite factories.酚醛塑料厂工人尿液中苯酚与大气中苯酚蒸气的定量关系。
Br J Ind Med. 1972;29(1):70-3. doi: 10.1136/oem.29.1.70.
7
Quantitative analysis of urinary glycine conjugates by high performance liquid chromatography: excretion of hippuric acid and methylhippuric acids in the urine of subjects exposed to vapours of toluene and xylenes.高效液相色谱法对尿中甘氨酸结合物的定量分析：接触甲苯和二甲苯蒸气的受试者尿液中马尿酸和甲基马尿酸的排泄情况
Int Arch Occup Environ Health. 1986;58(2):121-9. doi: 10.1007/BF00380763.
8
High performance liquid chromatography for the quantitative determination of urinary phenylsulfate and phenylglucuronide as indices of benzene and phenol exposure in rats.
Int Arch Occup Environ Health. 1979;44(3):177-84. doi: 10.1007/BF00381132.