Arif Mobeena, Radakovitz Joseph, Kulkarni Pallavi, Hepburn Iryna
Family Medicine Residency Program, WellSpan Good Samaritan Hospital, Lebanon, USA.
Family Medicine, Philadelphia College of Osteopathic Medicine, Philadelphia, USA.
Cureus. 2023 Aug 14;15(8):e43465. doi: 10.7759/cureus.43465. eCollection 2023 Aug.
We discuss the case of a 79-year-old immunocompetent male who presented with weight loss and diarrhea and ultimately was found to have a rectosigmoid mass on a colonoscopy. Even though initial biopsies obtained during colonoscopy were non-diagnostic, considering the likelihood of malignancy, lower anterior resection was performed, and pathology confirmed the diagnosis of primary Hodgkin's lymphoma of the sigmoid colon. Hodgkin's lymphoma typically presents as painless supra-diaphragmatic lymphadenopathy with B symptoms such as fever, unexplained weight loss, and drenching night sweats. Due to the rarity of primary Hodgkin lymphoma in the colon and its non-specific initial presentation, we believe sharing this case will bring awareness to the atypical presentation of Hodgkin lymphomas.
我们讨论了一名79岁免疫功能正常男性的病例,该患者出现体重减轻和腹泻症状,最终在结肠镜检查中发现直肠乙状结肠有肿物。尽管结肠镜检查期间获取的初始活检结果未能确诊,但考虑到恶性肿瘤的可能性,还是进行了低位前切除术,病理检查确诊为乙状结肠原发性霍奇金淋巴瘤。霍奇金淋巴瘤通常表现为无痛性膈上淋巴结肿大,并伴有发热、不明原因体重减轻和盗汗等B症状。由于原发性结肠霍奇金淋巴瘤罕见且初始表现不具特异性,我们认为分享此病例将提高对霍奇金淋巴瘤非典型表现的认识。