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糖尿病酮症酸中毒诱发的与癫痫发作和急性肾衰竭相关的“可怕三联征”:1例罕见病例报告

Diabetic Ketoacidosis-Induced "Terrible Triad" Associated With Seizures and Acute Renal Failure: A Report of a Rare Case.

作者信息

Kavathia Shrenil, Kataria Sharvil, Patel Nirav, Patel Sagar

机构信息

Internal Medicine, Shri Jalaram Arogya Seva Trust Hospital, Meghraj, IND.

Internal Medicine, Siddhi Heart and Medical Hospital, Ahmedabad, IND.

出版信息

Cureus. 2023 Sep 14;15(9):e45214. doi: 10.7759/cureus.45214. eCollection 2023 Sep.

Abstract

We report a case of a 17-year-old male patient who came to the emergency department with abdominal pain, headaches for two days, lethargy, and Kussmaul breathing. Diabetic ketoacidosis (DKA) was diagnosed. The patient's clinical course was complicated with a severely elevated triglyceride (TG) level (25,585 mg/dL), acute pancreatitis, renal involvement, and generalized seizures. The proposed mechanism is triglyceride excess due to increased lipolysis, resulting in the formation of excess free fatty acids. The objective of this case report is to present and describe the clinical features, laboratory investigations, case management, and natural course of hypertriglyceridemia in DKA.

摘要

我们报告一例17岁男性患者,该患者因腹痛、头痛两天、嗜睡和库斯莫尔呼吸前来急诊科就诊。诊断为糖尿病酮症酸中毒(DKA)。患者的临床病程并发严重升高的甘油三酯(TG)水平(25585mg/dL)、急性胰腺炎、肾脏受累和全身性癫痫发作。提出的机制是由于脂肪分解增加导致甘油三酯过量,从而形成过量的游离脂肪酸。本病例报告的目的是介绍和描述DKA中高甘油三酯血症的临床特征、实验室检查、病例管理和自然病程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c60f/10500620/f3aeaf449e11/cureus-0015-00000045214-i01.jpg

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