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根据《精神障碍诊断与统计手册》评估老年人失眠障碍的流行病学:系统回顾和荟萃分析。

Epidemiology of insomnia disorder in older persons according to the Diagnostic and Statistical Manual of Mental Disorders: a systematic review and meta-analysis.

机构信息

Research department, Medical Mind Association, Yaoundé, Cameroon.

Sleep Specialized Transversal Training, Psychiatry Internship Program, University of Burgundy, Dijon, France.

出版信息

Eur Geriatr Med. 2023 Dec;14(6):1261-1272. doi: 10.1007/s41999-023-00862-2. Epub 2023 Sep 19.

DOI:10.1007/s41999-023-00862-2
PMID:37725311
Abstract

PURPOSE

There is a scarcity of summarizing data on the epidemiology of insomnia in older persons, especially when diagnosed with international criteria. This study aimed to estimate the prevalence and correlates of insomnia disorder in older persons, according to the Diagnostic and Statistical Manual of Mental Disorders (DSM).

METHODS

Through PubMed/MEDLINE, EMBASE, and Web of Science (WoS), we searched for relevant articles published before June 28, 2023. The risk of bias was weighed using the Joanna Briggs Institute's (JBI's) critical appraisal checklist for studies reporting prevalence data. For our analyses, we used a random-effect model, with subgroup analyses, meta-regression, and sensitivity analyses to explore potential sources of heterogeneity. We followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement.

RESULTS

We included 18,270 participants across 16 studies. The male/female ratio was 0.89 (12 studies), and the mean age varied from 65.9 to 83.1 years (8 studies). The pooled prevalence of insomnia was 19.6% (95% CI = [12.3%; 28.3%]), with substantial heterogeneity. This prevalence fluctuated according to the sample size, the minimal age for inclusion, and the study quality, considering that the risk of bias was moderate for most of studies. There was a publication bias, with a very low level of certainty. Insomnia disorder was associated with the female gender, depression, anxiety, and somatic illnesses notably cardiovascular, respiratory, and painful ones.

CONCLUSION

Nearly one in every five old individuals was considered to have insomnia disorder, which was associated with the gender and the existence of mental health and/or somatic conditions.

REGISTRATION

We registered the protocol in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number: CRD42022344675.

摘要

目的

老年人失眠症的流行病学数据总结相对较少,特别是按照国际标准诊断时。本研究旨在根据《精神障碍诊断与统计手册》(DSM)估计老年人失眠症的患病率及其相关因素。

方法

通过 PubMed/MEDLINE、EMBASE 和 Web of Science(WoS),我们检索了截至 2023 年 6 月 28 日之前发表的相关文章。使用 Joanna Briggs 研究所(JBI)的流行性病学研究偏倚风险评估工具评估了研究报告患病率数据的风险偏倚。我们使用随机效应模型进行分析,包括亚组分析、meta 回归和敏感性分析,以探索潜在的异质性来源。我们遵循了系统评价和荟萃分析的首选报告项目声明。

结果

我们纳入了 16 项研究的 18270 名参与者。男性/女性比例为 0.89(12 项研究),平均年龄从 65.9 岁到 83.1 岁(8 项研究)。失眠的总患病率为 19.6%(95%CI=[12.3%;28.3%]),存在较大的异质性。该患病率随样本量、纳入的最小年龄和研究质量而波动,考虑到大多数研究的偏倚风险为中度,存在发表偏倚,且置信度非常低。失眠症与女性性别、抑郁、焦虑以及心血管、呼吸和疼痛等躯体疾病有关。

结论

近五分之一的老年人被认为患有失眠症,这与性别以及心理健康和/或躯体疾病的存在有关。

注册

我们在国际前瞻性系统评价注册库(PROSPERO)注册了该方案,注册编号为 CRD42022344675。

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