School of Materials Science and Engineering, Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic Materials, Shaanxi University of Science and Technology, Xi'an 710021, People's Republic of China.
Biomed Mater. 2023 Oct 3;18(6). doi: 10.1088/1748-605X/acfbd0.
This paper focuses on the preparation of Zn-doped TaOnanorods on porous tantalum using the hydrothermal method. Porous tantalum is widely used in biomedical materials due to its excellent elastic modulus and biological activity. Porous tantalum has an elastic modulus close to that of human bone, and its large specific surface area is conducive to promoting cell adhesion. Zinc is an important component of human bone, which not only has spectral bactericidal properties, but also has no cytotoxicity. The purpose of this study is to provide a theoretical basis for the surface modification of porous tantalum and to determine the best surface modification method. The surface structure of the sample was characterized by x-ray diffractometer, x-ray photoelectron spectroscopy, scanning electron microscope, transmission electron microscope, and the Zn-doped TaOnanorods are characterized by antibacterial test, MTT test, ICP and other methods. The sample has good antibacterial properties and no cytotoxicity. The results of this study have potential implications for the development of new and improved biomedical materials.
本文采用水热法在多孔钽上制备了掺锌 TaOnanorods。多孔钽由于其优异的弹性模量和生物活性而被广泛应用于生物医学材料。多孔钽的弹性模量与人骨相近，其较大的比表面积有利于促进细胞黏附。锌是人体骨骼的重要组成部分，它不仅具有光谱杀菌性能，而且没有细胞毒性。本研究旨在为多孔钽的表面改性提供理论依据，并确定最佳的表面改性方法。通过 X 射线衍射仪、X 射线光电子能谱、扫描电子显微镜、透射电子显微镜等方法对样品的表面结构进行了表征，采用抗菌试验、MTT 试验、ICP 等方法对掺锌 TaOnanorods 进行了表征。结果表明，该样品具有良好的抗菌性能且无细胞毒性。本研究结果对新型和改进型生物医学材料的开发具有潜在意义。
