• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项针对基层医疗中脆性骨折患者骨保护药物处方的五年回顾性审计。

A Five-Year Retrospective Audit on Bone Protection Prescribing in Patients With Fragility Fractures in Primary Care.

作者信息

Redman Ishtar A, Sivanesan Vicnesan

机构信息

General Practice, Ealing Hospital, London North West University Healthcare NHS Trust, London, GBR.

General Practice, The Mansell Road Practice, London, GBR.

出版信息

Cureus. 2023 Sep 19;15(9):e45532. doi: 10.7759/cureus.45532. eCollection 2023 Sep.

DOI:10.7759/cureus.45532
PMID:37731682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10507999/
Abstract

Background Fragility fractures typically occur in the elderly population due to low-energy trauma in the context of underlying osteoporotic bone disease. These fractures are becoming increasingly more common as the population of the United Kingdom ages, representing a significant public health issue. In the community, a joint care approach is adopted between general practitioners and fracture liaison services for the management of patients with fragility fractures. Despite this, preventive care for these patients remains substandard. This project aimed to conduct an audit of patients with a coded diagnosis of a fragility fracture in our primary care practice to ascertain fracture type and the prescription of bone protective agents. When necessary, the appropriate therapy was commenced per best practice guidelines. Methodology A search of patients with the diagnosis of on our electronic patient database, SystmOne, was conducted for the period of April 2019 to April 2023 inclusive. A retrospective audit of electronic patient records was done to identify patient demographic data, fracture types and dates, osteoporosis prescriptions, vitamin D/calcium supplementation, and bone densitometry scan results (dual-energy X-ray absorptiometry). Results A total of 47 patients were identified with a coded diagnosis of a , of whom 36 were females and 11 were males. The average age of the patients was 76.89 years with a range of 50 to 97. In total, 49 fractures were identified. More than two-thirds of the fractures identified were either distal forearm or neck of femur fractures (18 and 15, respectively). Of the 47 patients identified, 33 were on bone protection agents. Further, 26 received both bisphosphonates and calcium/vitamin D supplementation. Seven patients were on bisphosphonate monotherapy, and the remaining two patients were on vitamin D/calcium supplementation alone. Of the 47 patients, 12 had neither form of therapy prescribed. Conclusions Despite the joint effort between fracture liaison services and general practitioners, the secondary prevention of fragility fractures within the community remains inadequate. Fragility fractures are associated with significant morbidity, mortality, and re-fracture rates and incur significant costs to the National Health Service. Local practitioners must routinely evaluate their data to identify opportunities to improve patient care. Effective and timely treatment could be key to the prevention of new or second fractures.

摘要

背景 脆性骨折通常发生在老年人群中,是由于潜在骨质疏松性骨病背景下的低能量创伤所致。随着英国人口老龄化,这些骨折越来越常见,成为一个重大的公共卫生问题。在社区中,全科医生和骨折联络服务机构采用联合护理方法来管理脆性骨折患者。尽管如此,对这些患者的预防性护理仍未达标准。本项目旨在对我们基层医疗实践中编码诊断为脆性骨折的患者进行审核,以确定骨折类型和骨保护剂的处方情况。必要时,根据最佳实践指南开始适当的治疗。方法 对我们的电子患者数据库SystmOne中2019年4月至2023年4月(含)期间诊断为[此处原文缺失具体诊断内容]的患者进行搜索。对电子患者记录进行回顾性审核,以确定患者人口统计学数据、骨折类型和日期、骨质疏松症处方、维生素D/钙补充剂以及骨密度扫描结果(双能X线吸收法)。结果 共识别出47例编码诊断为[此处原文缺失具体诊断内容]的患者,其中36例为女性,11例为男性。患者的平均年龄为76.89岁,范围为50至97岁。总共识别出49处骨折。识别出的骨折中超过三分之二为前臂远端或股骨颈骨折(分别为18处和15处)。在识别出的47例患者中,33例正在使用骨保护剂。此外,26例同时接受双膦酸盐和钙/维生素D补充剂治疗。7例患者接受双膦酸盐单药治疗,其余2例患者仅接受维生素D/钙补充剂治疗。在47例患者中,12例未开具任何一种治疗药物。结论 尽管骨折联络服务机构和全科医生共同努力,但社区内脆性骨折的二级预防仍然不足。脆性骨折与显著的发病率、死亡率和再骨折率相关,并给国民医疗服务体系带来巨大成本。当地从业者必须定期评估他们的数据,以确定改善患者护理的机会。有效且及时的治疗可能是预防新骨折或二次骨折的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/68d6ad9289f0/cureus-0015-00000045532-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/f853a2c76545/cureus-0015-00000045532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/d0f4cbe1d178/cureus-0015-00000045532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/520c8488c8a3/cureus-0015-00000045532-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/554e174aba88/cureus-0015-00000045532-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/68d6ad9289f0/cureus-0015-00000045532-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/f853a2c76545/cureus-0015-00000045532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/d0f4cbe1d178/cureus-0015-00000045532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/520c8488c8a3/cureus-0015-00000045532-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/554e174aba88/cureus-0015-00000045532-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e2/10507999/68d6ad9289f0/cureus-0015-00000045532-i05.jpg

相似文献

1
A Five-Year Retrospective Audit on Bone Protection Prescribing in Patients With Fragility Fractures in Primary Care.一项针对基层医疗中脆性骨折患者骨保护药物处方的五年回顾性审计。
Cureus. 2023 Sep 19;15(9):e45532. doi: 10.7759/cureus.45532. eCollection 2023 Sep.
2
Utilization of DXA Bone Mineral Densitometry in Ontario: An Evidence-Based Analysis.安大略省双能X线吸收法骨密度测定的应用:基于证据的分析。
Ont Health Technol Assess Ser. 2006;6(20):1-180. Epub 2006 Nov 1.
3
Rates of osteoporosis screening and treatment following vertebral fracture.椎体骨折后骨质疏松症的筛查和治疗率。
Spine J. 2019 Mar;19(3):411-417. doi: 10.1016/j.spinee.2018.08.004. Epub 2018 Aug 22.
4
Rush Fracture Liaison Service for capturing "missed opportunities" to treat osteoporosis in patients with fragility fractures.脆性骨折联络服务,以捕捉治疗脆性骨折患者骨质疏松症的“错失机会”。
Osteoporos Int. 2018 Aug;29(8):1861-1874. doi: 10.1007/s00198-018-4559-9. Epub 2018 Jun 4.
5
Declining trend in osteoporosis management and screening following vertebral compression fractures - a national analysis of commercial insurance and medicare advantage beneficiaries.骨质疏松症管理和筛查在椎体压缩性骨折后的下降趋势 - 商业保险和医疗保险优势受益人的全国分析。
Spine J. 2020 Apr;20(4):538-546. doi: 10.1016/j.spinee.2019.10.020. Epub 2019 Nov 1.
6
Improving Osteoporosis Management in Primary Care: An Audit of the Impact of a Community Based Fracture Liaison Nurse.改善基层医疗中的骨质疏松症管理:一项关于社区骨折联络护士影响的审计
PLoS One. 2015 Aug 27;10(8):e0132146. doi: 10.1371/journal.pone.0132146. eCollection 2015.
7
Incidence of bone protection and associated fragility injuries in patients with proximal femur fractures.股骨近端骨折患者的骨保护及相关脆性损伤发生率。
Injury. 2017 Dec;48 Suppl 7:S27-S33. doi: 10.1016/j.injury.2017.08.035. Epub 2017 Aug 26.
8
Secondary prevention of fragility fractures: are we following the guidelines? Closing the audit loop.脆性骨折的二级预防:我们是否遵循了指南?完善审核环节。
Ann R Coll Surg Engl. 2006 Sep;88(5):470-4. doi: 10.1308/003588406X116891.
9
Closing the osteoporosis management gap in primary care: a secondary prevention of fracture programme.缩小初级保健中骨质疏松症管理的差距:一项骨折二级预防计划。
Curr Med Res Opin. 2005 Apr;21(4):475-82. doi: 10.1185/030079905X38150.
10
Radiology reporting of osteoporotic vertebral fragility fractures on computed tomography studies: results of a UK national audit.计算机断层扫描研究中骨质疏松性椎体脆性骨折的放射学报告:英国全国审计结果
Eur Radiol. 2020 Sep;30(9):4713-4723. doi: 10.1007/s00330-020-06845-2. Epub 2020 May 20.

引用本文的文献

1
A Retrospective Audit of Osteoporosis Management Following Fragility Fractures in a Hospital Setting.医院环境中脆性骨折后骨质疏松症管理的回顾性审计
Cureus. 2024 Dec 19;16(12):e76047. doi: 10.7759/cureus.76047. eCollection 2024 Dec.

本文引用的文献

1
A 3-year retrospective analysis of patients admitted with clinical vertebral fragility fractures across hospitals in England, UK.英国英格兰多家医院收治的有临床椎体脆性骨折患者的 3 年回顾性分析。
Osteoporos Int. 2023 Mar;34(3):607-611. doi: 10.1007/s00198-022-06647-w. Epub 2023 Jan 6.
2
Fragility fracture identifies patients at imminent risk for subsequent fracture: real-world retrospective database study in Ontario, Canada.脆性骨折可识别出随后有骨折风险的患者:加拿大安大略省的真实世界回顾性数据库研究。
BMC Musculoskelet Disord. 2021 Feb 26;22(1):224. doi: 10.1186/s12891-021-04051-9.
3
Bisphosphonate Drug Holidays in Primary Care: When and What to Do Next?
双膦酸盐药物停药期在初级保健中的应用:何时及下一步该做什么?
Curr Osteoporos Rep. 2021 Apr;19(2):182-188. doi: 10.1007/s11914-021-00660-4. Epub 2021 Feb 2.
4
Risk of imminent fracture following a previous fracture in a Swedish database study.在一项瑞典数据库研究中,既往骨折后发生骨折的风险。
Osteoporos Int. 2019 Mar;30(3):601-609. doi: 10.1007/s00198-019-04852-8. Epub 2019 Jan 24.
5
The Ability of a Single BMD and Fracture History Assessment to Predict Fracture Over 25 Years in Postmenopausal Women: The Study of Osteoporotic Fractures.一项研究骨质疏松性骨折的研究显示,单次骨密度和骨折史评估对预测绝经后妇女 25 年内骨折的能力。
J Bone Miner Res. 2018 Mar;33(3):389-395. doi: 10.1002/jbmr.3194. Epub 2017 Jul 18.
6
An overview and management of osteoporosis.骨质疏松症概述与管理
Eur J Rheumatol. 2017 Mar;4(1):46-56. doi: 10.5152/eurjrheum.2016.048. Epub 2016 Dec 30.
7
Impact of hip fracture on hospital care costs: a population-based study.髋部骨折对医院护理费用的影响:一项基于人群的研究。
Osteoporos Int. 2016 Feb;27(2):549-58. doi: 10.1007/s00198-015-3277-9. Epub 2015 Aug 19.
8
Denosumab for the treatment of osteoporosis.地诺单抗用于治疗骨质疏松症。
Expert Opin Drug Metab Toxicol. 2015 Mar;11(3):461-70. doi: 10.1517/17425255.2015.1000860. Epub 2015 Jan 22.
9
Denosumab: mechanism of action and clinical outcomes.地舒单抗:作用机制与临床结局。
Int J Clin Pract. 2012 Dec;66(12):1139-46. doi: 10.1111/ijcp.12022. Epub 2012 Sep 12.
10
Adverse effects of bisphosphonates.双膦酸盐的不良反应。
Calcif Tissue Int. 2010 Jun;86(6):421-35. doi: 10.1007/s00223-010-9364-1. Epub 2010 Apr 21.