埃及妇女生殖期 COVID-19 对精神的影响与胎儿结局的相关性。
Correlation between psychiatric impact of COVID-19 during pregnancy and fetal outcomes in Egyptian women.
机构信息
Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt; Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK.
Department of Obstetrics and Gynaecology, Faculty of Medicine, Assiut University, Assiut, Egypt.
出版信息
Psychiatry Res. 2022 Nov;317:114920. doi: 10.1016/j.psychres.2022.114920. Epub 2022 Oct 26.
The prevalence of depression, anxiety, and post-traumatic stress disorder (PTSD) was examined in 238 pregnant women with (n = 146) and without (n = 92) coronavirus disease 2019 (COVID-19) using the State-Trait Anxiety Inventory (STAI), Edinburgh Postnatal Depression Scale (EPDS), and PTSD Checklist for DSM-5 (PCL-5). Fetal outcomes in the same groups were evaluated using the Apgar score. Anxiety and depression scores were significantly higher in women with COVID-19 but PTSD scores were similar in both groups. Infection with COVID-19 was associated with a higher number of fetal deaths or an Apgar score <7. During the COVID-19 pandemic, approximately 46.6% of pregnant women had depression, 5.5% had PTSD, 64.3% had state anxiety, and 60.9% had trait anxiety. Except for PTSD, psychiatric problems and poor fetal outcomes were higher in women with COVID-19 than in those without COVID-19. Lastly, women with COVID-19 were more prone to have a fetus who died or had an Apgar score of <7.
本研究使用状态-特质焦虑量表（STAI）、爱丁堡产后抑郁量表（EPDS）和 DSM-5 创伤后应激障碍检查表（PCL-5），调查了 238 名孕妇（COVID-19 组 146 名，对照组 92 名）中抑郁、焦虑和创伤后应激障碍（PTSD）的患病率。使用阿普加评分评估两组的胎儿结局。COVID-19 组的焦虑和抑郁评分显著高于对照组，但 PTSD 评分在两组间相似。COVID-19 感染与胎儿死亡或阿普加评分<7 有关。在 COVID-19 大流行期间，约 46.6%的孕妇患有抑郁症，5.5%患有 PTSD，64.3%有状态焦虑，60.9%有特质焦虑。除 PTSD 外，COVID-19 孕妇的精神问题和不良胎儿结局发生率高于无 COVID-19 孕妇。最后，COVID-19 孕妇更易出现死胎或阿普加评分<7。
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