Editorial: toxicogenomics (TGx) in hazard and risk assessment.
作者信息
Beal Marc A, Everett Logan J
机构信息
Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada.
Biomolecular and Computational Toxicology Division, Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Durham, NC, United States.
出版信息
Front Toxicol. 2023 Sep 5;5:1284932. doi: 10.3389/ftox.2023.1284932. eCollection 2023.
Abstract
摘要
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本文引用的文献
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Evaluation of 5-day In Vivo Rat Liver and Kidney With High-throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes.高通量转录组学评价大鼠 5 天体内肝、肾，用于估算顶极终点的基准剂量。
Toxicol Sci. 2020 Aug 1;176(2):343-354. doi: 10.1093/toxsci/kfaa081.
2
A Rat Liver Transcriptomic Point of Departure Predicts a Prospective Liver or Non-liver Apical Point of Departure.大鼠肝脏转录组起始点可预测潜在的肝脏或非肝脏顶端起始点。
Toxicol Sci. 2020 Jul 1;176(1):86-102. doi: 10.1093/toxsci/kfaa062.
3
Accelerating the Pace of Chemical Risk Assessment.加速化学风险评估步伐。
Chem Res Toxicol. 2018 May 21;31(5):287-290. doi: 10.1021/acs.chemrestox.7b00339. Epub 2018 Apr 6.
4
Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs.开发和验证高通量转录组生物标志物以满足 21 世纪遗传毒理学的需求。
Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10881-E10889. doi: 10.1073/pnas.1714109114. Epub 2017 Dec 4.
5
Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse.编辑亮点：三氯乙烯和四氯乙烯在 B6C3F1 小鼠肝脏和肾脏转录组效应的比较剂量反应分析。
Toxicol Sci. 2017 Nov 1;160(1):95-110. doi: 10.1093/toxsci/kfx165.
6
Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells.利用剂量优化和信息学策略在人类细胞中开发用于遗传毒性的毒理基因组学特征。
Environ Mol Mutagen. 2015 Jul;56(6):505-19. doi: 10.1002/em.21941. Epub 2015 Mar 2.
7
Temporal concordance between apical and transcriptional points of departure for chemical risk assessment.用于化学风险评估的起始转录点和起始化学点之间的时间一致性。
Toxicol Sci. 2013 Jul;134(1):180-94. doi: 10.1093/toxsci/kft094. Epub 2013 Apr 17.
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