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草药、顺势疗法和常规牙膏对龋齿的疗效 - 一项双盲随机对照试验。

Effectiveness of Herbal, Homeopathic and Conventional Dentifrices on Dental Caries - A Double-Blind Randomised Controlled Trial.

出版信息

Oral Health Prev Dent. 2023 Sep 22;21:307-312. doi: 10.3290/j.ohpd.b4424883.

DOI:10.3290/j.ohpd.b4424883
PMID:37737306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11619875/
Abstract

PURPOSE

To compare the effectiveness of ayurvedic, homeopathic and conventional dentifrices on plaque and saliva in terms of cariogenic bacteria, salivary pH, and plaque pH.

MATERIALS AND METHODS

This double-blinded, parallel-group, randomised controlled trial was performed at Saveetha Dental College and Hospitals, Chennai, India. The participants comprised healthy adults possessing more than 20 permanent natural teeth and having a Decayed Missing and Filled Teeth (DMFT) score, plaque index score, and gingival index score less than or equal to 2. There were 3 intervention groups: 1: herbal dentifrice (Dabur Meswak); 2: homeopathic dentifrice (Gum Forte gel); 3: fluoride dentifrice (Colgate Total). The outcome measures were as follows: plaque and saliva samples were evaluated for pH; colony counts of Streptococcus mutans and Lactobacillus at baseline, 14 and 28 days of follow-up. One-way and repeated measures ANOVA, Wilcoxon signed-rank and Kruskal Wallis tests were used to compare the mean differences of plaque and salivary pH and plaque and salivary S. mutans and Lactobacillus counts at baseline, 14 and 28 days.

RESULTS

The mean S. mutans and Lactobacillus counts in plaque and saliva decreased statistically significantly in all treatment groups at the 28-day follow-up. Mean plaque pH was not statistically significantly different at the 14-day follow-up (p-value = 0.16). On the 28th day, group 1 (7.64 ± 0.20) showed the highest increase in plaque pH followed by group 2 (7.39 ± 0.25) and group 3 (7.27 ± 0.19), which was found to be statistically significant. No statistically significant difference in mean salivary pH was observed between the three groups at the different time points.

CONCLUSION

This study reveals that the herbal dentifrice tested here was effective in reducing cariogenic bacterial count and increasing the plaque pH, thereby warranting the usage of the same.

摘要

目的

比较阿育吠陀、顺势疗法和常规牙膏在菌斑和唾液方面对致龋细菌、唾液 pH 值和菌斑 pH 值的效果。

材料和方法

这是一项在印度钦奈的 Saveetha 牙科医学院和医院进行的双盲、平行组、随机对照试验。参与者包括健康成年人,他们拥有超过 20 颗恒牙,并且其患龋状况(DMFT)评分、菌斑指数评分和牙龈指数评分均小于或等于 2。干预组有 3 组:1:草药牙膏(Dabur Meswak);2:顺势疗法牙膏(Gum Forte 凝胶);3:含氟牙膏(高露洁全效)。评估的结果测量如下:菌斑和唾液样本评估 pH 值;基线、14 天和 28 天随访时变形链球菌和乳酸杆菌的菌落计数。使用单因素和重复测量方差分析、Wilcoxon 符号秩检验和 Kruskal-Wallis 检验比较菌斑和唾液 pH 值以及菌斑和唾液变形链球菌和乳酸杆菌计数的平均差异。

结果

所有治疗组在 28 天随访时,菌斑和唾液中的变形链球菌和乳酸杆菌计数均有统计学意义的降低。在 14 天随访时,菌斑 pH 值无统计学意义的差异(p 值=0.16)。在第 28 天,第 1 组(7.64±0.20)显示出最高的菌斑 pH 值增加,其次是第 2 组(7.39±0.25)和第 3 组(7.27±0.19),这具有统计学意义。在不同时间点,三组之间的平均唾液 pH 值无统计学差异。

结论

本研究表明,这里测试的草药牙膏在减少致龋细菌数量和增加菌斑 pH 值方面是有效的,因此值得使用。

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