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康复运动在改善慢性创伤性脑病方面的益处:最新进展和未来展望。

The benefits of rehabilitation exercise in improving chronic traumatic encephalopathy: recent advances and future perspectives.

机构信息

Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Quanzhou, 362000, Fujian, China.

Centre of Neurological and Metabolic Research, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Quanzhou, 362000, Fujian, China.

出版信息

Mol Med. 2023 Sep 22;29(1):131. doi: 10.1186/s10020-023-00728-0.

Abstract

Traumatic encephalopathy syndrome (TES) is used to describe the clinical manifestations of chronic traumatic encephalopathy (CTE). However, effective treatment and prevention strategies are lacking. Increasing evidence has shown that rehabilitation training could prevent cognitive decline, enhance brain plasticity, and effectively improve neurological function in neurodegenerative diseases. Therefore, the mechanisms involved in the effects of rehabilitation exercise therapy on the prognosis of CTE are worth exploring. The aim of this article is to review the pathogenesis of CTE and provide a potential clinical intervention strategy for CTE.

摘要

创伤性脑疾病综合征(TES)用于描述慢性创伤性脑病(CTE)的临床表现。然而,目前缺乏有效的治疗和预防策略。越来越多的证据表明,康复训练可以预防认知能力下降,增强大脑可塑性,并有效改善神经退行性疾病的神经功能。因此,康复运动疗法对 CTE 预后的影响机制值得探讨。本文旨在综述 CTE 的发病机制,并为 CTE 提供一种潜在的临床干预策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbc8/10517475/6e9c50922e47/10020_2023_728_Fig1_HTML.jpg

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