Bhagwasia Manjusha, Rao Abhijith R, Banerjee Joyita, Bajpai Swati, Raman Aruna V, Talukdar Arunanshu, Jain Arvind, Rajguru Chhaya, Sankhe Lalit, Goswami Debabrata, Shanthi Ganapathy Sankaralingam, Kumar Govind, Varghese Mathew, Dhar Minakshi, Gupta Monica, A-Koul Parvaiz, Mohanty Rashmi Ranjan, Chakrabarti Sankha Shubhra, Yadati Sathyanarayana Raju, Dey Sharmistha, Dey Aparajit Ballav
All India Institute of Medical Sciences, New Delhi, India.
Venu Geriatric Institute, New Delhi, India.
Gerontol Geriatr Med. 2023 Sep 20;9:23337214231194965. doi: 10.1177/23337214231194965. eCollection 2023 Jan-Dec.
Malnutrition in low- and middle-income countries causes cognitive decline and other health problems. Harmonized Diagnostic Assessment of Dementia for Longitudinal Aging Study in India (LASI DAD) is an extensive study on late-life cognition and dementia. This study examines the link between nutrition and cognitive abilities in older adults using data from the LASI DAD. We conducted descriptive statistics on nutritional parameters (body-mass index, waist-hip ratio, and Mini-Nutritional Assessment), cognitive functions, and socio-demographic variables in 2,892 adults aged ≥60 years. Cognitive domains assessed included delayed recall, orientation, language, executive function, abstract reasoning, and attention. Cognitive impairment was defined as impaired performance in two or more domains. Mean age was 69.3 ± 7.1 years, 52.9% were female, and 57.5% were illiterate. Low body-mass index (adjusted OR: 1.88, < .001), at risk of malnutrition (adjusted OR: 1.89, < .001) and malnourished (adjusted OR: 2.86, < .001) on Mini-Nutritional Assessment were associated with the presence of cognitive impairment. Better cognitive performance was associated with increased body mass index (adjusted OR: 0.74, -.03), hemoglobin (adjusted OR: 0.91, -.006), and serum albumin (adjusted OR: 0.38, < .001). This study shows that nutritional status assessed by anthropometric measures and blood markers is strongly linked to cognitive performance in older adults.
低收入和中等收入国家的营养不良会导致认知能力下降和其他健康问题。印度纵向衰老研究痴呆症统一诊断评估（LASI DAD）是一项关于晚年认知和痴呆症的广泛研究。本研究利用LASI DAD的数据，探讨了老年人营养与认知能力之间的联系。我们对2892名年龄≥60岁的成年人的营养参数（体重指数、腰臀比和小型营养评估）、认知功能和社会人口统计学变量进行了描述性统计。评估的认知领域包括延迟回忆、定向、语言、执行功能、抽象推理和注意力。认知障碍被定义为在两个或更多领域的表现受损。平均年龄为69.3±7.1岁，52.9%为女性，57.5%为文盲。小型营养评估中低体重指数（调整后的OR：1.88，<0.001）、有营养不良风险（调整后的OR：1.89，<0.001）和营养不良（调整后的OR：2.86，<0.001）与认知障碍的存在相关。更好的认知表现与体重指数增加（调整后的OR：0.74，-0.03）、血红蛋白（调整后的OR：0.91，-0.006）和血清白蛋白（调整后的OR：0.38，<0.001）相关。这项研究表明，通过人体测量指标和血液标志物评估的营养状况与老年人的认知表现密切相关。
