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腹泻的罕见病因:一名HIV阳性患者的肠道螺旋体病

A Rare Cause of Diarrhea: Intestinal Spirochetosis in an HIV-Positive Patient.

作者信息

Falgout Lacey, Kailas Shilpa, Sridhar Supraja, Loganantharaj Nisha

机构信息

Department of Gastroenterology, Louisiana State University Health Sciences Center, New Orleans, LA.

出版信息

ACG Case Rep J. 2023 Sep 23;10(9):e01148. doi: 10.14309/crj.0000000000001148. eCollection 2023 Sep.

DOI:10.14309/crj.0000000000001148
PMID:37753098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10519532/
Abstract

Intestinal spirochetosis (IS) is a rare gastrointestinal infection with vague presenting symptoms. Diagnosis is confirmed histopathologically. Risk factors include homosexuality and HIV. Antibiotic treatment with metronidazole usually leads to resolution of symptoms. We present the case of a 56-year-old HIV-positive man with chronic, watery diarrhea who was diagnosed with IS. This case highlights the importance of considering IS in the differential in HIV-positive patients with nonspecific gastrointestinal symptoms after more common etiologies have been ruled out.

摘要

肠道螺旋体病(IS)是一种罕见的胃肠道感染,症状不明确。通过组织病理学确诊。危险因素包括同性恋和感染人类免疫缺陷病毒(HIV)。甲硝唑抗生素治疗通常可使症状缓解。我们报告一例56岁HIV阳性男性病例,该患者患有慢性水样腹泻,被诊断为肠道螺旋体病。该病例强调了在排除更常见病因后,对于有非特异性胃肠道症状的HIV阳性患者,在鉴别诊断中考虑肠道螺旋体病的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285f/10519532/9d6289507f2e/ac9-10-e01148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285f/10519532/2d58f8e10a0c/ac9-10-e01148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285f/10519532/9d6289507f2e/ac9-10-e01148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285f/10519532/2d58f8e10a0c/ac9-10-e01148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285f/10519532/9d6289507f2e/ac9-10-e01148-g002.jpg

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Intestinal Spirochetosis in an Immunocompetent Patient.免疫功能正常患者的肠道螺旋体病
Cureus. 2018 Mar 15;10(3):e2328. doi: 10.7759/cureus.2328.
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Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden.在瑞典的普通人群中,结肠螺旋体病与结肠嗜酸性粒细胞增多症和肠易激综合征有关。
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Rectal syphilis mimicking rectal cancer.直肠梅毒酷似直肠癌。
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Rapid and accurate diagnosis of human intestinal spirochetosis by fluorescence in situ hybridization.通过荧光原位杂交技术快速准确诊断人类肠道螺旋体病
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Rectal spirochaetosis in homosexual men: the association with sexual practices, HIV infection and enteric flora.男同性恋者的直肠螺旋体病:与性行为、HIV感染及肠道菌群的关联。
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