双胞胎早期发展研究（TEDS）：对二十多岁人群心理健康结果的一项基因敏感性调查。
Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties.
作者信息
Lockhart Celestine, Bright Joanna, Ahmadzadeh Yasmin, Breen Gerome, Bristow Shannon, Boyd Andy, Downs Johnny, Hotopf Matthew, Palaiologou Elisavet, Rimfeld Kaili, Maxwell Jessye, Malanchini Margherita, McAdams Tom A, McMillan Andrew, Plomin Robert, Eley Thalia C
机构信息
Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience King's College London Camberwell London UK.
UK National Institute for Health Research (NIHR) Biomedical Research Centre South London and Maudsley Hospital London UK.
出版信息
JCPP Adv. 2023 Mar 30;3(2):e12154. doi: 10.1002/jcv2.12154. eCollection 2023 Jun.
The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.
双胞胎早期发展研究（TEDS）是一项纵向研究，跟踪调查1994年至1996年在英格兰和威尔士出生的一批双胞胎。在最初同意参与研究的13759个家庭中，超过10000个家庭仍在参与该研究。TEDS目前的重点是二十多岁时的心理健康。利用超过25年的基因敏感数据，TEDS在探索成年早期常见心理健康障碍的纵向遗传和环境影响方面具有独特的优势。本文概述了支持这项工作的近期数据收集工作，包括26岁时全队列心理健康评估和多阶段新冠疫情研究。它还将提供数据链接工作和TEDS儿童（CoTEDS）项目的最新情况。
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