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基于多任务注意力的神经网络用于术中低血压预测

Multitask Attention-Based Neural Network for Intraoperative Hypotension Prediction.

作者信息

Shi Meng, Zheng Yu, Wu Youzhen, Ren Quansheng

机构信息

School of Electronics, Peking University, Beijing 100871, China.

College of Engineering, Peking University, Beijing 100871, China.

出版信息

Bioengineering (Basel). 2023 Aug 31;10(9):1026. doi: 10.3390/bioengineering10091026.

DOI:10.3390/bioengineering10091026
PMID:37760128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10525858/
Abstract

Timely detection and response to Intraoperative Hypotension (IOH) during surgery is crucial to avoid severe postoperative complications. Although several methods have been proposed to predict IOH using machine learning, their performance still has space for improvement. In this paper, we propose a ResNet-BiLSTM model based on multitask training and attention mechanism for IOH prediction. We trained and tested our proposed model using bio-signal waveforms obtained from patient monitoring of non-cardiac surgery. We selected three models (WaveNet, CNN, and TCN) that process time-series data for comparison. The experimental results demonstrate that our proposed model has optimal MSE (43.83) and accuracy (0.9224) compared to other models, including WaveNet (51.52, 0.9087), CNN (318.52, 0.5861), and TCN (62.31, 0.9045), which suggests that our proposed model has better regression and classification performance. We conducted ablation experiments on the multitask and attention mechanisms, and the experimental results demonstrated that the multitask and attention mechanisms improved MSE and accuracy. The results demonstrate the effectiveness and superiority of our proposed model in predicting IOH.

摘要

手术过程中及时检测并应对术中低血压(IOH)对于避免严重的术后并发症至关重要。尽管已经提出了几种使用机器学习预测IOH的方法,但其性能仍有提升空间。在本文中,我们提出了一种基于多任务训练和注意力机制的ResNet-BiLSTM模型用于IOH预测。我们使用从非心脏手术患者监测中获得的生物信号波形对我们提出的模型进行训练和测试。我们选择了三种处理时间序列数据的模型(WaveNet、CNN和TCN)进行比较。实验结果表明,与其他模型相比,我们提出的模型具有最优的均方误差(MSE,43.83)和准确率(0.9224),包括WaveNet(51.52,0.9087)、CNN(318.52,0.5861)和TCN(62.31,0.9045),这表明我们提出的模型具有更好的回归和分类性能。我们对多任务和注意力机制进行了消融实验,实验结果表明多任务和注意力机制提高了MSE和准确率。结果证明了我们提出的模型在预测IOH方面的有效性和优越性。

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引用本文的文献

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Predictive ability of hypotension prediction index and machine learning methods in intraoperative hypotension: a systematic review and meta-analysis.低血压预测指数和机器学习方法在术中低血压预测中的预测能力:系统评价和荟萃分析。
J Transl Med. 2024 Aug 5;22(1):725. doi: 10.1186/s12967-024-05481-4.

本文引用的文献

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Cuff-Less Blood Pressure Prediction Based on Photoplethysmography and Modified ResNet.基于光电容积脉搏波描记法和改进残差网络的无袖带血压预测
Bioengineering (Basel). 2023 Mar 24;10(4):400. doi: 10.3390/bioengineering10040400.
2
Estimating the Depth of Anesthesia from EEG Signals Based on a Deep Residual Shrinkage Network.基于深度残差收缩网络的脑电信号麻醉深度估算。
Sensors (Basel). 2023 Jan 15;23(2):1008. doi: 10.3390/s23021008.
3
Predicting intraoperative hypotension using deep learning with waveforms of arterial blood pressure, electroencephalogram, and electrocardiogram: Retrospective study.
基于动脉血压、脑电图和心电图波形的深度学习预测术中低血压:回顾性研究。
PLoS One. 2022 Aug 9;17(8):e0272055. doi: 10.1371/journal.pone.0272055. eCollection 2022.
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4D attention-based neural network for EEG emotion recognition.用于脑电图情感识别的基于4D注意力的神经网络。
Cogn Neurodyn. 2022 Aug;16(4):805-818. doi: 10.1007/s11571-021-09751-5. Epub 2022 Jan 3.
5
Intraoperative Hypotension Prediction Model Based on Systematic Feature Engineering and Machine Learning.基于系统特征工程和机器学习的术中低血压预测模型。
Sensors (Basel). 2022 Apr 19;22(9):3108. doi: 10.3390/s22093108.
6
Short-Term Event Prediction in the Operating Room (STEP-OP) of Five-Minute Intraoperative Hypotension Using Hybrid Deep Learning: Retrospective Observational Study and Model Development.基于混合深度学习的手术室五分钟术中低血压短期事件预测(STEP-OP):回顾性观察研究与模型开发
JMIR Med Inform. 2021 Sep 30;9(9):e31311. doi: 10.2196/31311.
7
Deep learning models for the prediction of intraoperative hypotension.深度学习模型在术中低血压预测中的应用。
Br J Anaesth. 2021 Apr;126(4):808-817. doi: 10.1016/j.bja.2020.12.035. Epub 2021 Feb 6.
8
Generalizable deep temporal models for predicting episodes of sudden hypotension in critically ill patients: a personalized approach.可推广的深度时间模型用于预测危重病患者突发性低血压发作:个性化方法。
Sci Rep. 2020 Jul 10;10(1):11480. doi: 10.1038/s41598-020-67952-0.
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Association of intra-operative hypotension with acute kidney injury, myocardial injury and mortality in non-cardiac surgery: A meta-analysis.术中低血压与非心脏手术患者急性肾损伤、心肌损伤和死亡率的关系:一项荟萃分析。
Int J Clin Pract. 2019 Oct;73(10):e13394. doi: 10.1111/ijcp.13394. Epub 2019 Sep 11.
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