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与神经退行性疾病相关的睡眠障碍

Sleep Disorders Associated with Neurodegenerative Diseases.

作者信息

Anghel Lucreția, Ciubară Anamaria, Nechita Aurel, Nechita Luiza, Manole Corina, Baroiu Liliana, Ciubară Alexandru Bogdan, Mușat Carmina Liana

机构信息

Clinical Medical Department, Faculty of Medicine and Pharmacy, 'Dunarea de Jos' University, 800008 Galati, Romania.

'Sf. Apostol Andrei' Clinical Emergency County Hospital, 800578 Galati, Romania.

出版信息

Diagnostics (Basel). 2023 Sep 10;13(18):2898. doi: 10.3390/diagnostics13182898.

Abstract

Sleep disturbances are common in various neurological pathologies, including amyotrophic lateral sclerosis (ALS), multiple system atrophy (MSA), hereditary ataxias, Huntington's disease (HD), progressive supranuclear palsy (PSP), and dementia with Lewy bodies (DLB). This article reviews the prevalence and characteristics of sleep disorders in these conditions, highlighting their impact on patients' quality of life and disease progression. Sleep-related breathing disorders, insomnia, restless legs syndrome (RLS), periodic limb movement syndrome (PLMS), and rapid eye movement sleep behavior disorder (RBD) are among the common sleep disturbances reported. Both pharmacological and non-pharmacological interventions play crucial roles in managing sleep disturbances and enhancing overall patient care.

摘要

睡眠障碍在各种神经疾病中很常见,包括肌萎缩侧索硬化症(ALS)、多系统萎缩症(MSA)、遗传性共济失调、亨廷顿舞蹈症(HD)、进行性核上性麻痹(PSP)以及路易体痴呆(DLB)。本文综述了这些病症中睡眠障碍的患病率和特征,强调了它们对患者生活质量和疾病进展的影响。睡眠相关呼吸障碍、失眠、不宁腿综合征(RLS)、周期性肢体运动综合征(PLMS)以及快速眼动睡眠行为障碍(RBD)是报告中常见的睡眠障碍。药物和非药物干预在管理睡眠障碍及加强整体患者护理方面都起着关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fec2/10527657/efd9522c4049/diagnostics-13-02898-g001.jpg

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